Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 3/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296382 | 0.92 | ESR1 (0.63) | ESR1ESR2HTR6DHFR | |
| SCHEMBL296770 | 0.92 | ESR1 (0.63) | ESR1ESR2CCR2DHFR | |
| SCHEMBL30295754 | 0.92 | ESR1 (0.63) | ESR1ESR2HTR6DHFR | |
| SCHEMBL21538491 | 0.80 | ESR1 (0.69) | ESR1ESR2 | |
| SCHEMBL244496 | 0.77 | ESR1 (0.65) | ESR1ESR2CCR2 | |
| SCHEMBL29404012 | 0.77 | ESR1 (0.65) | ESR1ESR2CCR2 | |
| SCHEMBL29459501 | 0.77 | ESR1 (0.65) | ESR1ESR2CCR2 | |
| SCHEMBL296906 | 0.77 | ESR1 (0.59) | ESR1ESR2 | |
| SCHEMBL298455 | 0.77 | ESR1 (0.59) | ESR1ESR2CCR2 | |
| SCHEMBL7909628 | 0.76 | ESR1 (0.63) | ESR1ESR2CCR2DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763560-B1 | POLYARYLATE COMPOSITIONS | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-08-26 | — | — | EP | disclosed |