Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423725 | 0.95 | ALDH1A1 (0.52) | ALDH1A1HPGDTRPV1EPHX2PTGS2 | |
| SCHEMBL1499598 | 0.79 | SMN1; SMN2 (0.68) | ALDH1A1TRPV1EPHX2MAPTABL1 | |
| SCHEMBL15392837 | 0.78 | ABL1 (0.63) | TRPV1EPHX2MAPTABL1TDP1 | |
| SCHEMBL12377315 | 0.75 | EPHX2 (0.73) | ALDH1A1HPGDTRPV1EPHX2MAPT | |
| SCHEMBL551897 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HPGDTDP1MEN1KMT2A | |
| SCHEMBL1346717 | 0.71 | EPHX2 (0.58) | ALDH1A1TRPV1EPHX2TDP1MEN1 | |
| SCHEMBL12225782 | 0.71 | NPC1 (0.69) | ALDH1A1HPGDTRPV1EPHX2MAPT | |
| SCHEMBL1496356 | 0.71 | TRPV1 (0.59) | TRPV1EPHX2TLR8MAPTABL1 | |
| SCHEMBL4664426 | 0.71 | KDM4E (0.51) | TRPV1NPC1RAB9A | |
| SCHEMBL551896 | 0.70 | ALDH1A1 (0.47) | ALDH1A1HPGDTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362369-B1 | — | — | None | — | — | US | disclosed |
| EP-1700844-B1 | Phthalic acid diamide derivatives, agricultural and horticultural insecticides and a method for application of the insecticides | NIHON NOHYAKU CO LTD (JP) | 2009-01-14 | — | — | EP | disclosed |
| EP-1447396-A1 | Phthalic acid diamide derivatives, agriculture and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO., LTD. (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6559341-B2 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO., LTD. (JP) | 2003-05-06 | — | — | US | disclosed |
| US-20030055287-A1 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | AIR MOTION TECHNOLOGIES, LLC | 2003-03-20 | — | — | US | disclosed |
| US-6362369-B2 | CONTROLLING INSECTS IN CROPS | NIHON NOHYAKU CO., LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-20010041814-A1 | PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-0919542-A2 | Phthalic acid diamide derivatives, agricultural and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO., LTD. (JP) | 1999-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041814-A1 | PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES | DDT, AFF1, BCL2L2 | ALDH1A1 252/4885HPGD 3918/4885TRPV1 3150/4885 |
| US-20030055287-A1 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | DDT, BCL2A1, BCL2L2 | ALDH1A1 269/4885HPGD 3799/4885TRPV1 3037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.