Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1381716 | 0.87 | KDM4E (0.54) | KDM4ENPC1RAB9ATRPV1 | |
| SCHEMBL3973134 | 0.84 | ABL1 (0.49) | TRPV1 | |
| SCHEMBL3191191 | 0.80 | LMNA (0.48) | NPC1RAB9ATRPV1 | |
| SCHEMBL4662798 | 0.80 | NPSR1 (0.52) | KDM4E | |
| SCHEMBL13702138 | 0.79 | MLYCD (0.65) | NPC1RAB9ATRPV1 | |
| SCHEMBL14263664 | 0.76 | SMN1; SMN2 (0.46) | KDM4E | |
| SCHEMBL7561932 | 0.75 | KDM4E (0.49) | KDM4ENPC1RAB9ATRPV1 | |
| SCHEMBL3981465 | 0.73 | MAPT (0.49) | NPC1RAB9ATRPV1 | |
| SCHEMBL1382114 | 0.73 | LMNA (0.54) | NPC1RAB9A | |
| SCHEMBL4425763 | 0.71 | ALDH1A1 (0.49) | NPC1RAB9ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1700845-B1 | Insecticidal anthranilamides | DU PONT (US) | 2008-12-10 | — | — | EP | disclosed |
| US-7338978-B2 | Insecticidal anthranilamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| EP-1265850-B1 | INSECTICIDAL ANTHRANILAMIDES | DU PONT (US) | 2007-01-03 | — | — | EP | disclosed |
| EP-1700845-A1 | Insecticidal anthranilamides | E.I.Du pont de nemours and company (US) | 2006-09-13 | — | — | EP | disclosed |
| US-20060079561-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2006-04-13 | — | — | US | disclosed |
| US-6995178-B2 | Insecticidal anthranilamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-02-07 | — | — | US | disclosed |
| US-20040142984-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2004-07-22 | — | — | US | disclosed |
| US-6747047-B2 | ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-06-08 | — | — | US | disclosed |
| US-20030229050-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2003-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142984-A1 | Insecticidal anthranilamides | ANTXR2, NIT2, AKR7A2 | KDM4E 1178/4885NPC1 3052/4885RAB9A 240/4885 |
| US-20060079561-A1 | Insecticidal anthranilamides | ANTXR2, CYB5R3, NIT2 | KDM4E 1284/4885NPC1 3193/4885RAB9A 407/4885 |
| US-20030229050-A1 | Insecticidal anthranilamides | ANTXR2, NIT2, CYB5R3 | KDM4E 1313/4885NPC1 3299/4885RAB9A 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.