Urea

Urea

SCHEMBL4425912

CCCCn1cnnc1.NC(N)=O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 3/20 0.38
CPB1 P15086 1/20 0.38
TBXAS1 P24557 1/20 0.37
GAA P10253 1/20 0.34
USP2 O75604 1/20 0.33
MEN1 O00255 1/20 0.33
HSP90AA1 P07900 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TOP2A P11388 1/20 0.33
CNR1 P21554 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
PDE4A P27815 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14247 0.87
Water SCHEMBL29031201 0.84 TBXAS1 (0.43) TBXAS1MEN1HSP90AA1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL29031198 0.84 TBXAS1 (0.43) TBXAS1MEN1HSP90AA1KMT2ASMN1; SMN2
SCHEMBL2364458 0.80 TBXAS1 (0.54) TBXAS1GAAMEN1HSP90AA1KMT2A
SCHEMBL2408764 0.78 TBXAS1 (0.39) TBXAS1HSP90AA1KMT2ASMN1; SMN2TOP2A
SCHEMBL1820999 0.78 TBXAS1 (0.57) TBXAS1MEN1HSP90AA1KMT2ASMN1; SMN2
SCHEMBL10981743 0.78 TBXAS1 (0.57) TBXAS1MEN1HSP90AA1KMT2ASMN1; SMN2
SCHEMBL11376133 0.78 TBXAS1 (0.57) TBXAS1MEN1HSP90AA1KMT2ASMN1; SMN2
SCHEMBL20441199 0.78 TBXAS1 (0.57) TBXAS1MEN1HSP90AA1KMT2ASMN1; SMN2
SCHEMBL11369087 0.78 TBXAS1 (0.57) TBXAS1MEN1HSP90AA1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799776-A4 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS OSMOSE INC (US) 2009-05-06 EP disclosed
EP-1799776-A2 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS Osmose, Inc. (US) 2007-06-27 EP disclosed
WO-2006044831-A2 NON-ALKALINE MICRONIZED WOOD PRESERVATIVE FORMULATIONS OSMOSE, INC. (US) 2006-04-27 WO disclosed
WO-2006044218-A2 MICRONIZED WOOD PRESERVATIVE FORMULATIONS IN ORGANIC CARRIERS OSMOSE, INC. (US) 2006-04-27 WO disclosed