Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | HTT | P42858 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GALR3 | O60755 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376133 | 0.97 | TBXAS1 (0.57) | TBXAS1NPC1RAB9AHTTLMNA | |
| SCHEMBL20441199 | 0.97 | TBXAS1 (0.57) | TBXAS1NPC1RAB9AHTTLMNA | |
| SCHEMBL11369087 | 0.97 | TBXAS1 (0.57) | TBXAS1NPC1RAB9AHTTLMNA | |
| SCHEMBL1820999 | 0.97 | TBXAS1 (0.57) | TBXAS1NPC1RAB9AHTTLMNA | |
| SCHEMBL10981743 | 0.97 | TBXAS1 (0.57) | TBXAS1NPC1RAB9AHTTLMNA | |
| SCHEMBL14247 | 0.92 | — | — | |
| Water SCHEMBL29031201 | 0.90 | TBXAS1 (0.43) | TBXAS1NPC1RAB9AHTTLMNA | |
| Hydrochloric Acid SCHEMBL29031198 | 0.90 | TBXAS1 (0.43) | TBXAS1NPC1RAB9AHTTLMNA | |
| SCHEMBL23316952 | 0.84 | TBXAS1 (0.46) | TBXAS1NPC1RAB9AHTTLMNA | |
| SCHEMBL19413109 | 0.84 | TBXAS1 (0.46) | TBXAS1NPC1RAB9AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585241-A | AT2R antagonists and uses thereof | 伊莱利利公司 | 2025-03-07 | — | — | CN | disclosed |
| US-20250074875-A1 | AT2R ANTAGONISTS AND USES THEREOF | ELI LILLY AND COMPANY | 2025-03-06 | — | — | US | disclosed |
| US-12122750-B2 | AT2R antagonists and uses thereof | ELI LILLY AND COMPANY (US) | 2024-10-22 | — | — | US | disclosed |
| US-20240231230-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM | NISSAN CHEMICAL CORPORATION (JP) | 2024-07-11 | — | — | US | disclosed |
| US-20230373919-A1 | AT2R ANTAGONISTS AND USES THEREOF | ELI LILLY AND COMPANY | 2023-11-23 | — | — | US | disclosed |
| US-20230373919-A1 | AT2R ANTAGONISTS AND USES THEREOF | ELI LILLY AND COMPANY | 2023-11-23 | — | — | US | disclosed |
| WO-2023224853-A1 | AT2R ANTAGONISTS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023224853-A1 | AT2R ANTAGONISTS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023086638-A1 | ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |
| US-20210147408-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB CO (US) | 2021-05-20 | — | — | US | disclosed |
| US-7989579-B2 | mixing hydrazine salts with dicarboxylic acids or derivatives in polyphosphoric acid, then heating, adding primary amines to the solution to form polyhydrazides and precipitating poly(1,2,4-triazole)-polymers from the solution; fibers and membranes for use in fuel cells | GKSS-FORSCHUNGSZENTRUM GEESTHACHT GMBH (DE) | 2011-08-02 | — | — | US | disclosed |
| US-20100168376-A1 | PRODUCTION OF A FUNCTIONALIZED POLYTRIAZOLE POLYMER | GKSS-FORSCHUNGSZENTRUM GEESTHACHT GMBH (DE) | 2010-07-01 | — | — | US | disclosed |
| EP-1953186-B1 | Manufacture of a functionalised polytriazol polymer | GEESTHACHT GKSS FORSCHUNG (DE) | 2009-09-02 | — | — | EP | disclosed |
| EP-1953186-A1 | Manufacture of a functionalised polytriazol polymer | GKSS-FORSCHUNGSZENTRUM GEESTHACHT GMBH (DE) | 2008-08-06 | — | — | EP | disclosed |
| US-20080182964-A1 | PRODUCTION OF A FUNCTIONALIZED POLYTRIAZOLE POLYMER | GKSS-FORSCHUNGSZENTRUM GEESTHACHT GMBH (DE) | 2008-07-31 | — | — | US | disclosed |
| US-4519940-A | CONTAINING DOPED 1,3,4-TRIAZOLE RINGS | CHEVRON RESEARCH COMPANY (US) | 1985-05-28 | — | — | US | disclosed |
| EP-0065217-A2 | 5-Haloalkyl-1,2,4-triazole and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-24 | — | — | EP | disclosed |
| US-4271308-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| EP-0011693-A1 | N-trifluoromethane-sulfonylaminophenyl-substituted N-heterocycles, their preparation, compositions containing them and their use in regulating plant growth | CIBA-GEIGY AG (CH) | 1980-06-11 | — | — | EP | disclosed |
| US-4120864-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147408-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | LGALS3, LGALS1, LGALS3BP | TBXAS1 2538/4885NPC1 1772/4885RAB9A 1654/4885 |
| US-20230373919-A1 | AT2R ANTAGONISTS AND USES THEREOF | AGTR2, AGTR1, AVPR2 | TBXAS1 550/4885NPC1 2373/4885RAB9A 2255/4885 |
| US-20250074875-A1 | AT2R ANTAGONISTS AND USES THEREOF | AGTR2, AGTR1, AVPR2 | TBXAS1 524/4885NPC1 2406/4885RAB9A 2273/4885 |
| US-12122750-B2 | AT2R antagonists and uses thereof | AGTR2, AGTR1, AVPR2 | TBXAS1 550/4885NPC1 2373/4885RAB9A 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.