Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 5/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426251 | 0.84 | EDNRA (0.40) | EDNRAAGTR1EDNRB | |
| SCHEMBL4423450 | 0.80 | EDNRA (0.41) | EDNRAAGTR1EDNRB | |
| SCHEMBL30517192 | 0.78 | EDNRA (0.38) | EDNRAAGTR1EDNRB | |
| SCHEMBL4291679 | 0.78 | EDNRA (0.43) | EDNRAAGTR1EDNRB | |
| SCHEMBL31498371 | 0.77 | EDNRA (0.38) | EDNRAAGTR1EDNRB | |
| SCHEMBL31498369 | 0.77 | EDNRA (0.38) | EDNRAAGTR1EDNRB | |
| SCHEMBL535104 | 0.77 | EDNRA (0.43) | EDNRAAGTR1EDNRB | |
| SCHEMBL30757240 | 0.77 | EDNRA (0.43) | EDNRAAGTR1EDNRB | |
| SCHEMBL30757327 | 0.77 | EDNRA (0.43) | EDNRAAGTR1EDNRB | |
| SCHEMBL30757382 | 0.77 | EDNRA (0.38) | EDNRAAGTR1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155448-A1 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |