SCHEMBL442642

SCHEMBL442642

CCC1C(=O)OC(=O)CC1C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.34
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13560764 0.79 ALDH1A1 (0.36) ALDH1A1TSHRSMN1; SMN2LMNA
SCHEMBL13891803 0.75 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL14539088 0.75 ALDH1A1 (0.36) ALDH1A1TSHRLMNA
SCHEMBL3398190 0.75 ALDH1A1 (0.36) ALDH1A1TSHRLMNA
SCHEMBL9843832 0.73 ALDH1A1 (0.33) ALDH1A1TSHRLMNA
SCHEMBL8870956 0.73 SMN1; SMN2 (0.40) ALDH1A1TSHRSMN1; SMN2
SCHEMBL14845387 0.72 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL15095428 0.71 MEN1 (0.31) SMN1; SMN2LMNA
SCHEMBL20208292 0.71 MEN1 (0.31) SMN1; SMN2LMNA
SCHEMBL2759295 0.71 MEN1 (0.31) SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110160390-A1 PROCESS FOR PRODUCTION OF POLYESTERS WITH LOW ACETALDEHYDE CONTENT AND REGENERATION RATE INVISTA NORTH AMERICA S.AR.L (US) 2011-06-30 US claimed
WO-2010026361-A1 PROCESS FOR PRODUCTION OF POLYESTERS WITH LOW ACETALDEHYDE CONTENT AND REGENERATION RATE INVISTA TECHNOLOGIES S.A.R.L. (CH) 2010-03-11 WO claimed
EP-1716206-A4 REACTIVE CARRIERS FOR POLYMER MELT INJECTION INVISTA TECH SARL (CH) 2008-03-19 EP claimed
EP-1716206-A2 REACTIVE CARRIERS FOR POLYMER MELT INJECTION Invista North America, S.a.r.l. (US) 2006-11-02 EP claimed
US-7087706-B2 Polyester with high carboxyl end groups and methods for making INVISTA NORTH AMERICA, S.A.R.L (US) 2006-08-08 US claimed
WO-2005076947-A2 REACTIVE CARRIERS FOR POLYMER MELT INJECTION INVISTA TECHNOLOGIES S.À.R.L. (LU) 2005-08-25 WO claimed
US-20050176920-A1 Polyester with high carboxyl end groups and methods for making INVISTA TEXTILES (U.K.) LIMITED (GB) 2005-08-11 US claimed
US-20050176881-A1 Reactive carriers for polymer melt injection INVISTA NORTH AMERICA S.A.R.L. 2005-08-11 US claimed
CN-112831033-B Method for synthesizing aromatic-aliphatic copolyester without catalyst and product thereof 浙江大学 2022-03-22 CN disclosed
EP-3126424-B1 ALIPHATIC POLYCARBONATE POLYOL COMPOSITIONS SAUDI ARAMCO TECH CO (SA) 2020-09-30 EP disclosed
CN-106661215-B Aliphatic polycarbonate polyol composition 沙特阿美技术公司 2020-09-22 CN disclosed
US-10308759-B2 Aliphatic polycarbonate polyol compositions SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2019-06-04 US disclosed
US-9872935-B2 Hydrogel implants with varying degrees of crosslinking COVIDIEN LP (US) 2018-01-23 US disclosed
EP-3031446-B1 HYDROGEL IMPLANTS WITH VARYING DEGREES OF CROSSLINKING COVIDIEN LP (US) 2017-09-13 EP disclosed
US-7294671-B2 Reactive carriers for polymer melt injection INVISTA NORTH AMERICA S.A.R.L. (US) 2007-11-13 US disclosed
EP-1716206-A2 REACTIVE CARRIERS FOR POLYMER MELT INJECTION Invista North America, S.a.r.l. (US) 2006-11-02 EP disclosed
US-7087706-B2 Polyester with high carboxyl end groups and methods for making INVISTA NORTH AMERICA, S.A.R.L (US) 2006-08-08 US disclosed
WO-2005076947-A2 REACTIVE CARRIERS FOR POLYMER MELT INJECTION INVISTA TECHNOLOGIES S.À.R.L. (LU) 2005-08-25 WO disclosed
US-20050176920-A1 Polyester with high carboxyl end groups and methods for making INVISTA TEXTILES (U.K.) LIMITED (GB) 2005-08-11 US disclosed
US-20050176881-A1 Reactive carriers for polymer melt injection INVISTA NORTH AMERICA S.A.R.L. 2005-08-11 US disclosed