Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 8/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.34 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.34 |
| ▸ | GSR | P00390 | 2/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL1253823 | 1.00 | SLC1A1 (0.41) | SLC1A1PTGS1SLC7A11GRIK1GRIK2 | |
| Serine SCHEMBL3185132 | 0.85 | SLC1A1 (0.52) | SLC1A1PTGS1SLC7A11GRIK1GRIK2 | |
| Serine SCHEMBL3185153 | 0.79 | SLC1A1 (0.46) | SLC1A1PTGS1SLC7A11GRIK1GRIK2 | |
| Serine SCHEMBL3185148 | 0.79 | SLC1A1 (0.46) | SLC1A1PTGS1SLC7A11GRIK1GRIK2 | |
| Serine SCHEMBL1332181 | 0.78 | — | — | |
| Serine SCHEMBL6520912 | 0.78 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11GRIK1GRIK2 | |
| Serine SCHEMBL6929773 | 0.78 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11GRIK1GRIK2 | |
| Serine SCHEMBL4455818 | 0.78 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11GRIK1GRIK2 | |
| (D)-Serine SCHEMBL6038168 | 0.78 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11GRIK1GRIK2 | |
| (D)-Serine SCHEMBL6660617 | 0.78 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4681778-A2 | COMBINATION THERAPIES BASED ON PD1 AND IL-17B INHIBITORS | Orega Biotech (FR) | 2026-01-21 | — | — | EP | disclosed |
| EP-3946377-B1 | COMBINATION THERAPIES BASED ON PD1 AND IL-17B INHIBITORS | OREGA BIOTECH (FR) | 2025-12-10 | — | — | EP | disclosed |
| US-20230045494-A1 | COMBINATION THERAPIES BASED ON CTLA4 AND IL-17B INHIBITORS | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2023-02-09 | — | — | US | disclosed |
| EP-4110810-A1 | COMBINATION THERAPIES BASED ON CTLA4 AND IL-17B INHIBITORS | Orega Biotech (FR) | 2023-01-04 | — | — | EP | disclosed |
| US-20220281967-A1 | NOVEL IL-17B ANTIBODIES | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2022-09-08 | — | — | US | disclosed |
| US-20220175815-A1 | COMBINATION THERAPIES BASED ON PD1 AND IL-17B INHIBITORS | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2022-06-09 | — | — | US | disclosed |
| EP-3946377-A1 | COMBINATION THERAPIES BASED ON PD1 AND IL-17B INHIBITORS | Orega Biotech (FR) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020201442-A1 | COMBINATION THERAPIES BASED ON PD1 AND IL-17B INHIBITORS | OREGA BIOTECH (FR) | 2020-10-08 | — | — | WO | disclosed |
| EP-2569335-B1 | METHODS OF TREATING AND/OR PREVENTING CELL PROLIFERATION DISORDERS WITH IL-17 ANTAGONISTS | OREGA BIOTECH (FR) | 2018-08-22 | — | — | EP | disclosed |
| US-20170233468-A1 | IL-17 ANTAGONIST ANTIBODIES | OREGA BIOTECH (FR) | 2017-08-17 | — | — | US | disclosed |
| EP-1708751-A4 | METHODS OF KILLING TUMOR CELLS BY TARGETING INTERNAL ANTIGENS EXPOSED ON APOPTOTIC TUMOR CELLS | VACCINEX INC (US) | 2007-11-07 | — | — | EP | disclosed |
| CN-1913921-A | Methods of killing tumor cells by targeting internal antigens exposed on apoptotic tumor cells | VACCINEX INC (US) | 2007-02-14 | — | — | CN | disclosed |
| EP-1708751-A2 | METHODS OF KILLING TUMOR CELLS BY TARGETING INTERNAL ANTIGENS EXPOSED ON APOPTOTIC TUMOR CELLS | Vaccinex, Inc. (US) | 2006-10-11 | — | — | EP | disclosed |
| US-20050158323-A1 | Methods of killing tumor cells by targeting internal antigens exposed on apoptotic tumor cells | VACCINEX, INC. (US) | 2005-07-21 | — | — | US | disclosed |
| WO-2005055936-A2 | METHODS OF KILLING TUMOR CELLS BY TARGETING INTERNAL ANTIGENS EXPOSED ON APOPTOTIC TUMOR CELLS | VACCINEX, INC. (US) | 2005-06-23 | — | — | WO | disclosed |
| US-20030114379-A1 | Methods of treating or preventing cell, tissue, and organ damage using human myeloid progenitor inhibitory factor-1 (MPIF-1) | HUMAN GENOME SCIENCES, INC. | 2003-06-19 | — | — | US | disclosed |
| US-6495129-B1 | Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3) | HUMAN GENOME SCIENCES, INC. | 2002-12-17 | — | — | US | disclosed |
| WO-2001026676-A9 | METHODS OF TREATING OR PREVENTING CELL, TISSUE, AND ORGAN DAMAGE USING HUMAN MYELOID PROGENITOR INHIBITORY FACTOR-1 (MPIF-1) | HUMAN GENOME SCIENCES INC (US) | 2002-11-07 | — | — | WO | disclosed |
| EP-1225911-A1 | METHODS OF TREATING OR PREVENTING CELL, TISSUE, AND ORGAN DAMAGE USING HUMAN MYELOID PROGENITOR INHIBITORY FACTOR-1 (MPIF-1) | Human Genome Sciences (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001026676-A1 | METHODS OF TREATING OR PREVENTING CELL, TISSUE, AND ORGAN DAMAGE USING HUMAN MYELOID PROGENITOR INHIBITORY FACTOR-1 (MPIF-1) | HUMAN GENOME SCIENCES, INC. (US) | 2001-04-19 | — | — | WO | disclosed |