Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.39 |
| ▸ | GSR | P00390 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL3185148 | 1.00 | SLC1A1 (0.46) | SLC1A1PTGS1SLC7A11SLC1A3SLC1A2 | |
| Serine SCHEMBL3185132 | 0.93 | SLC1A1 (0.52) | SLC1A1PTGS1SLC7A11SLC1A3SLC1A2 | |
| (D)-Serine SCHEMBL43094 | 0.84 | — | — | |
| Serine SCHEMBL1332181 | 0.84 | — | — | |
| Serine SCHEMBL6520918 | 0.84 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11SLC1A3SLC1A2 | |
| (D)-Serine SCHEMBL6038168 | 0.84 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11SLC1A3SLC1A2 | |
| Serine SCHEMBL6929773 | 0.84 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11SLC1A3SLC1A2 | |
| Serine SCHEMBL4455818 | 0.84 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11SLC1A3SLC1A2 | |
| Serine SCHEMBL6520912 | 0.84 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11SLC1A3SLC1A2 | |
| (D)-Serine SCHEMBL6660617 | 0.84 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061519-B1 | CLICK CHEMISTRY-DERIVED CYCLOPEPTIDE DERIVATIVES AS IMAGING AGENTS FOR INTEGRINS | SIEMENS MEDICAL SOLUTIONS (US) | 2016-03-30 | — | — | EP | disclosed |
| US-7666392-B2 | Click chemistry-derived cyclopeptide derivatives as imaging agents for integrins | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| EP-2061519-A2 | CLICK CHEMISTRY-DERIVED CYCLOPEPTIDE DERIVATIVES AS IMAGING AGENTS FOR INTEGRINS | Siemens Medical Solutions USA, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20080170992-A1 | Click chemistry-derived cyclopeptide derivatives as imaging agents for integrins | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2008-07-17 | — | — | US | disclosed |
| WO-2008033561-A2 | CLICK CHEMISTRY-DERIVED CYCLOPEPTIDE DERIVATIVES AS IMAGING AGENTS FOR INTEGRINS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| US-5710245-A | Alpha-helix mimetics and methods relating thereto | MOLECUMETICS, LTD. (US) | 1998-01-20 | — | — | US | disclosed |
| US-5446128-A | Stabilizers for alpha helix structure of natural or synthetic peptides or proteins | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1995-08-29 | — | — | US | disclosed |
| EP-0662079-A1 | ALPHA-HELIX MIMETICS AND METHODS RELATING THERETO | MOLECUMETICS, LTD. (US) | 1995-07-12 | — | — | EP | disclosed |
| WO-1995000534-A1 | ALPHA-HELIX MIMETICS AND METHODS RELATING THERETO | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1995-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080170992-A1 | Click chemistry-derived cyclopeptide derivatives as imaging agents for integrins | ITGB3, VCAM1, ITGB1 | SLC1A1 2180/4885PTGS1 3330/4885SLC7A11 2375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.