Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647478 | 0.94 | HTT (0.48) | WDR5KMT2AALDH1A1LMNAHTT | |
| SCHEMBL1644779 | 0.83 | HSD17B10 (0.49) | ALDH1A1HTTMAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL30464734 | 0.76 | ALDH1A1 (0.66) | WDR5KMT2AALDH1A1LMNAHTT | |
| SCHEMBL2461666 | 0.76 | ALDH1A1 (0.66) | WDR5KMT2AALDH1A1LMNAHTT | |
| SCHEMBL7803729 | 0.75 | HTT (0.60) | WDR5KMT2AALDH1A1LMNAHTT | |
| SCHEMBL1645633 | 0.74 | KDM4E (0.50) | WDR5KMT2AALDH1A1HTTMAPT | |
| SCHEMBL8689842 | 0.73 | HSD17B10 (0.49) | KMT2AALDH1A1MAPTMEN1KCNJ1 | |
| SCHEMBL28845817 | 0.73 | WDR5 (0.52) | WDR5KMT2AALDH1A1LMNAHTT | |
| SCHEMBL5557064 | 0.71 | WDR5 (0.66) | WDR5KMT2AALDH1A1LMNAHTT | |
| SCHEMBL28504649 | 0.71 | HTT (0.50) | WDR5KMT2AALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097413-A1 | 2-[(2-SUBSTITUTED)-IND0LIZIN-3-YL]-2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G Limited (GB) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008062182-A1 | 2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G LTD (GB) | 2008-05-29 | — | — | WO | disclosed |