SCHEMBL4426696

SCHEMBL4426696

[O]C(F)(F)C(F)(F)C(F)(F)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9482464 0.88
SCHEMBL66564 0.79
SCHEMBL15402187 0.78
SCHEMBL5169518 0.74
SCHEMBL1901612 0.73
SCHEMBL5493064 0.73
SCHEMBL45066 0.72 LMNA (0.30)
SCHEMBL865500 0.71
SCHEMBL292476 0.69 LMNA (0.35)
SCHEMBL19412161 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112080129-B Radiation-vulcanized thermoplastic polyurethane elastomer/fluororubber blending material and preparation method thereof 万华化学集团股份有限公司 2022-11-04 CN claimed
CN-112080130-B Thermoplastic polyurethane elastomer/fluororubber blending material and preparation method thereof 万华化学集团股份有限公司 2022-11-04 CN claimed
CN-112080130-A Thermoplastic polyurethane elastomer/fluororubber blending material and preparation method thereof 万华化学集团股份有限公司 2020-12-15 CN claimed
CN-112080129-A Radiation-vulcanized thermoplastic polyurethane elastomer/fluororubber blending material and preparation method thereof 万华化学集团股份有限公司 2020-12-15 CN claimed
US-8318209-B2 microspheres; inner core is polymethyl methacrylate hydrogel polymer and a contrast agent; outer polyphosphazene coating; poly[bis(2,2,2-trifluoroethoxy)phosphazene]; size of particle allows selective embolization of certain blood vessels; fluoroscopy, tomography CELONOVA BIOSCIENCES GERMANY GMBH (DE) 2012-11-27 US claimed
EP-0765871-B1 Substituted Quinoline-2-carboxamides, their preparation and their use as prolyle-4-hydroxylase Inhibitors FIBROGEN INC (US) 2004-03-31 EP claimed
EP-0765871-A1 Substituted Quinoline-2-carboxamides, their preparation and their use as prolyle-4-hydroxylase Inhibitors HOECHST AKTIENGESELLSCHAFT (DE) 1997-04-02 EP claimed
US-4956366-A GASTROINTESTINAL DISORDERS, ANTISECRETORY AGENTS FOR GASTRIC ACID SECRETION HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-11 US claimed
EP-0299389-A2 Substituted thieno-imidazole derivatives, process for their preparation, pharmaceutical compositions containing them and their use as gastric secretion inhibitors, gastric protecting agents and as medicaments against intestinal inflammation HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-18 EP claimed
US-20240209020-A1 REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE COMPOUND USING SAME CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2024-06-27 US disclosed
US-20230002422-A1 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2023-01-05 US disclosed
CN-112080130-B Thermoplastic polyurethane elastomer/fluororubber blending material and preparation method thereof 万华化学集团股份有限公司 2022-11-04 CN disclosed
CN-112080129-B Radiation-vulcanized thermoplastic polyurethane elastomer/fluororubber blending material and preparation method thereof 万华化学集团股份有限公司 2022-11-04 CN disclosed
CN-112080129-A Radiation-vulcanized thermoplastic polyurethane elastomer/fluororubber blending material and preparation method thereof 万华化学集团股份有限公司 2020-12-15 CN disclosed
EP-0400625-A2 Laminated films IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-12-05 EP disclosed
US-4956366-A GASTROINTESTINAL DISORDERS, ANTISECRETORY AGENTS FOR GASTRIC ACID SECRETION HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-11 US disclosed
US-4945139-A SOLVENT RESISTANCE, POLYPHOSPHAZINES ETHYL CORPORATION (US) 1990-07-31 US disclosed
EP-0365925-A1 Pyrazole amides and insecticide and miticide containing them as active ingredient Mitsubishi Chemical Corporation (JP) 1990-05-02 EP disclosed
EP-0299389-A2 Substituted thieno-imidazole derivatives, process for their preparation, pharmaceutical compositions containing them and their use as gastric secretion inhibitors, gastric protecting agents and as medicaments against intestinal inflammation HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-18 EP disclosed
US-4169960-A REMOVING WATER FROM FLUORINATED ALCOHOLS EMPLOYING A TETRAHYDROCARBYLAMMONIUM HYDROXIDE PHILLIPS PETROLEUM COMPANY (US) 1979-10-02 US disclosed