SCHEMBL4427288

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4422505	0.84	CFD (0.54)	HDAC8HDAC6HDAC1MAPTKMT2A
	SCHEMBL5449209	0.82	MAPT (0.58)	NPC1RAB9AMAPTGAANPSR1
	SCHEMBL8287820	0.82	BCHE (0.54)	BCHEACHENPC1RAB9AFLT3
	SCHEMBL8289907	0.81	HDAC6 (0.55)	NPC1RAB9AFLT3HDAC2HDAC8
	SCHEMBL4552859	0.80	CDK1 (0.57)	FLT3HDAC2HDAC8HDAC6HDAC1
	SCHEMBL21929513	0.78	L3MBTL1 (0.55)	BCHEACHENPC1RAB9AFLT3
	SCHEMBL4566820	0.78	BRD4 (0.53)	FLT3HDAC1AURKAHPGD
	SCHEMBL13426353	0.77	BCHE (0.56)	BCHEACHENPC1RAB9AKCNK3
	SCHEMBL5020210	0.77	KCNK3 (0.58)	BCHEACHEPARP1NPC1RAB9A
	SCHEMBL13426343	0.76	NR1H4 (0.56)	BCHEACHENPC1RAB9AFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.