Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427410 | 0.89 | CREBBP (0.61) | TRPV1CREBBP | |
| SCHEMBL4430324 | 0.89 | TRPV1 (0.62) | TRPV1CREBBP | |
| SCHEMBL4434512 | 0.87 | CREBBP (0.73) | TRPV1CREBBP | |
| SCHEMBL4422969 | 0.87 | TRPV1 (0.58) | TRPV1CREBBP | |
| SCHEMBL13998316 | 0.85 | TRPV1 (0.64) | TRPV1CREBBP | |
| SCHEMBL12992097 | 0.84 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4434239 | 0.81 | TRPV1 (0.61) | TRPV1CREBBP | |
| SCHEMBL12992503 | 0.79 | TRPV1 (0.91) | TRPV1 | |
| SCHEMBL4427423 | 0.79 | CREBBP (0.62) | TRPV1CREBBP | |
| SCHEMBL4424245 | 0.78 | CREBBP (0.61) | TRPV1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538121-B2 | Vanilloid receptor modulators | GLAXO GROUP LIMITED (GB) | 2009-05-26 | — | — | US | disclosed |
| US-7538121-B2 | Vanilloid receptor modulators | GLAXO GROUP LIMITED (GB) | 2009-05-26 | — | — | US | disclosed |
| EP-2033953-A1 | Vanilloid receptor modulators | Glaxo Group Limited (GB) | 2009-03-11 | — | — | EP | disclosed |
| EP-2033953-A1 | Vanilloid receptor modulators | Glaxo Group Limited (GB) | 2009-03-11 | — | — | EP | disclosed |
| EP-1480954-B1 | VANILLOID RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2008-12-03 | — | — | EP | disclosed |