Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 7/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.59 |
| ▸ | TEK | Q02763 | 4/20 | 0.49 |
| ▸ | ABL1 | P00519 | 4/20 | 0.49 |
| ▸ | BCR | P11274 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427342 | 0.89 | TRPV1 (0.72) | CREBBPTRPV1 | |
| SCHEMBL4427826 | 0.88 | CREBBP (0.64) | CREBBPTRPV1ABL1BCR | |
| SCHEMBL4422969 | 0.81 | TRPV1 (0.58) | CREBBPTRPV1 | |
| SCHEMBL4430324 | 0.81 | TRPV1 (0.62) | CREBBPTRPV1 | |
| SCHEMBL4434512 | 0.79 | CREBBP (0.73) | CREBBPTRPV1 | |
| SCHEMBL4429965 | 0.78 | CREBBP (0.59) | CREBBPTRPV1 | |
| SCHEMBL4434239 | 0.77 | TRPV1 (0.61) | CREBBPTRPV1 | |
| SCHEMBL13998316 | 0.76 | TRPV1 (0.64) | CREBBPTRPV1 | |
| SCHEMBL4427423 | 0.75 | CREBBP (0.62) | CREBBPTRPV1 | |
| SCHEMBL14083725 | 0.75 | TRPV1 (0.55) | CREBBPTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538121-B2 | Vanilloid receptor modulators | GLAXO GROUP LIMITED (GB) | 2009-05-26 | — | — | US | disclosed |
| US-7538121-B2 | Vanilloid receptor modulators | GLAXO GROUP LIMITED (GB) | 2009-05-26 | — | — | US | disclosed |
| EP-2033953-A1 | Vanilloid receptor modulators | Glaxo Group Limited (GB) | 2009-03-11 | — | — | EP | disclosed |
| EP-2033953-A1 | Vanilloid receptor modulators | Glaxo Group Limited (GB) | 2009-03-11 | — | — | EP | disclosed |
| EP-1480954-B1 | VANILLOID RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2008-12-03 | — | — | EP | disclosed |