Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 5/20 | 0.38 |
| ▸ | NOS1 | P29475 | 4/20 | 0.38 |
| ▸ | NOS3 | P29474 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 3/20 | 0.36 |
| ▸ | ARG2 | P78540 | 3/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Citrulline SCHEMBL8174334 | 0.92 | OTC (0.48) | OTCDDAH1NOS2NOS1NOS3 | |
| L-Citrulline SCHEMBL8174339 | 0.92 | OTC (0.48) | OTCDDAH1NOS2NOS1NOS3 | |
| L-Citrulline SCHEMBL17164652 | 0.83 | OTC (0.56) | OTCDDAH1NOS2NOS1NOS3 | |
| L-Citrulline SCHEMBL27840753 | 0.81 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| L-Citrulline SCHEMBL27840755 | 0.81 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| SCHEMBL9069162 | 0.81 | GSR (0.55) | OTCDDAH1NOS2NOS1NOS3 | |
| SCHEMBL5279090 | 0.81 | GSR (0.55) | OTCDDAH1NOS2NOS1NOS3 | |
| SCHEMBL56915 | 0.81 | GSR (0.55) | OTCDDAH1NOS2NOS1NOS3 | |
| SCHEMBL8871251 | 0.81 | GSR (0.55) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL5598764 | 0.81 | OTC (0.46) | OTCDDAH1NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2101571-A1 | NON-STANDARD AMINO ACID CONJUGATES OF AMPHETAMINE AND PROCESSES FOR MAKING AND USING THE SAME | Kempharm, Inc. (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008073918-A1 | NON-STANDARD AMINO ACID CONJUGATES OF AMPHETAMINE AND PROCESSES FOR MAKING AND USING THE SAME | KEMPHARM, INC. (US) | 2008-06-19 | — | — | WO | disclosed |