Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.48 |
| ▸ | DDAH1 | O94760 | 4/20 | 0.45 |
| ▸ | NOS2 | P35228 | 7/20 | 0.41 |
| ▸ | NOS1 | P29475 | 6/20 | 0.41 |
| ▸ | NOS3 | P29474 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GSR | P00390 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Citrulline SCHEMBL8174339 | 1.00 | OTC (0.48) | OTCDDAH1NOS2NOS1NOS3 | |
| L-Citrulline SCHEMBL4428049 | 0.92 | OTC (0.42) | OTCDDAH1NOS2NOS1NOS3 | |
| L-Citrulline SCHEMBL27840755 | 0.89 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| L-Citrulline SCHEMBL27840753 | 0.89 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL5598764 | 0.88 | OTC (0.46) | OTCDDAH1NOS2NOS1NOS3 | |
| L-Citrulline SCHEMBL215403 | 0.87 | OTC (0.59) | OTCDDAH1NOS2NOS1NOS3 | |
| L-Citrulline SCHEMBL15909604 | 0.87 | OTC (0.59) | OTCDDAH1NOS2NOS1NOS3 | |
| L-Citrulline SCHEMBL9070200 | 0.87 | OTC (0.59) | OTCDDAH1NOS2NOS1NOS3 | |
| L-Citrulline SCHEMBL20587 | 0.87 | OTC (0.59) | OTCDDAH1NOS2NOS1NOS3 | |
| L-Citrulline SCHEMBL22426116 | 0.87 | OTC (0.59) | OTCDDAH1NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043220-A | Threonine-containing protegrins | INTRABIOTICS PHARMACEUTICALS, INC. (US) | 2000-03-28 | — | — | US | disclosed |
| US-6025326-A | TOPICALLY ADMINISTERING TO ORAL CAVITY SELECTED ANTIMICROBIAL PEPTIDE | INTRABIOTICS PHARMACEUTICALS, INC. (US) | 2000-02-15 | — | — | US | disclosed |
| US-5994306-A | ANTIMICROBIAL PEPTIDE | INTRABIOTICS PHARMACEUTICALS, INC. (US) | 1999-11-30 | — | — | US | disclosed |