⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010227 | 0.73 | — | — | |
| SCHEMBL438270 | 0.73 | POLB (0.33) | — | |
| SCHEMBL1038844 | 0.73 | — | — | |
| SCHEMBL1898922 | 0.71 | — | — | |
| SCHEMBL3276351 | 0.69 | ABCG2 (0.36) | — | |
| SCHEMBL4413227 | 0.68 | POLB (0.31) | — | |
| SCHEMBL11227302 | 0.64 | MAOA (0.33) | — | |
| SCHEMBL3072276 | 0.64 | MAOA (0.46) | — | |
| SCHEMBL30094184 | 0.64 | BRD4 (0.41) | — | |
| SCHEMBL3195764 | 0.64 | BRD4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492431-B2 | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity | JANSSEN PHARMACEUTICA, N.V. (BE) | 2013-07-23 | — | — | US | claimed |
| US-20120065257-A1 | USE OF BENZO-FUSED HETEROCYLE SULFAMIDE DERIVATIVES FOR THE TREATMENT OF MIGRAINE | SMITH-SWINTOSKY VIRGINIA L (US) | 2012-03-15 | — | — | US | claimed |