SCHEMBL4428224

SCHEMBL4428224

CCCCCCCC/C=C\CCCCCCCCO[C@H](COC(=O)CCCCCCCCCCCCCCC)COC(C(O)CO)P(=O)(O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCE Q02156 1/20 0.56
PRKCQ Q04759 1/20 0.56
PRKCD Q05655 1/20 0.56
PRKCA P17252 1/20 0.56
DGKA P23743 1/20 0.56
ENPP2 Q13822 4/20 0.55
CNR1 P21554 1/20 0.54
CNR2 P34972 1/20 0.54
LPAR1 Q92633 7/20 0.53
LPAR3 Q9UBY5 4/20 0.53
LPAR4 Q99677 3/20 0.53
LPAR2 Q9HBW0 3/20 0.53
LPAR5 Q9H1C0 2/20 0.53
CES2 O00748 1/20 0.53
LPAR6 P43657 1/20 0.53
TRPV1 Q8NER1 1/20 0.53
SELP P16109 1/20 0.53
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
TDP1 Q9NUW8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7076073 0.91 PRKCA (0.67) PRKCEPRKCQPRKCDPRKCADGKA
SCHEMBL3403845 0.91 PRKCA (0.67) PRKCEPRKCQPRKCDPRKCADGKA
SCHEMBL1893444 0.91 PRKCA (0.67) PRKCEPRKCQPRKCDPRKCADGKA
SCHEMBL457068 0.91 PRKCA (0.67) PRKCEPRKCQPRKCDPRKCADGKA
SCHEMBL565670 0.91 PRKCA (0.67) PRKCEPRKCQPRKCDPRKCADGKA
SCHEMBL3408924 0.88 SELP (0.69) PRKCEPRKCQPRKCDPRKCADGKA
SCHEMBL2228662 0.87 SELP (0.68) PRKCEPRKCQPRKCDPRKCADGKA
SCHEMBL3274160 0.87 LPAR1 (0.53) CNR1CNR2LPAR1LPAR3LPAR2
SCHEMBL667267 0.87 LPAR1 (0.53) CNR1CNR2LPAR1LPAR3LPAR2
SCHEMBL4195003 0.86 PRKCA (0.60) PRKCEPRKCQPRKCDPRKCADGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2438086-B1 IMPROVED RECONSTITUTED SURFACTANT COMPOSITION CONTAINING ANALOGS OF SURFACTANT PROTEIN B (SP-B) AND SURFACTANT PROTEIN C (SP-C) CHIESI FARM SPA (IT) 2017-01-11 EP claimed
EP-1628634-B1 NOVEL LIPID MIXTURES FOR SYNTHETIC SURFACTANTS CHIESI FARMA SPA (IT) 2009-12-23 EP claimed