SCHEMBL3274160

SCHEMBL3274160

CCCCCCCC/C=C\CCCCCCCCOC[C@H](COC(C(O)CO)P(=O)(O)O)OCCCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ LPAR1 Q92633 7/20 0.53
▸ LPAR3 Q9UBY5 7/20 0.53
▸ ALDH1A1 P00352 1/20 0.49
▸ CNR1 P21554 1/20 0.49
▸ CNR2 P34972 1/20 0.49
▸ LPAR2 Q9HBW0 2/20 0.47
▸ P2RY10 O00398 2/20 0.46
▸ LPAR5 Q9H1C0 1/20 0.42
▸ USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL667267 1.00 LPAR1 (0.53) LPAR1LPAR3ALDH1A1CNR1CNR2
SCHEMBL10566866 0.93 LPAR1 (0.60) LPAR1LPAR3LPAR2LPAR5USP2
SCHEMBL10562812 0.93 LPAR1 (0.60) LPAR1LPAR3LPAR2LPAR5USP2
SCHEMBL2672057 0.93 LPAR1 (0.60) LPAR1LPAR3LPAR2LPAR5USP2
SCHEMBL753952 0.92 LPAR1 (0.58) LPAR1LPAR3LPAR2LPAR5USP2
SCHEMBL8902468 0.88 ALDH1A1 (0.51) LPAR1LPAR3ALDH1A1CNR1CNR2
SCHEMBL4428224 0.87 PRKCE (0.56) LPAR1LPAR3CNR1CNR2LPAR2
SCHEMBL10563457 0.84 LPAR1 (0.53) LPAR1LPAR3ALDH1A1LPAR2LPAR5
SCHEMBL17291865 0.83 LPAR1 (0.47) LPAR1LPAR3LPAR2LPAR5USP2
Ammonia Solution, Strong SCHEMBL6373587 0.83 LPAR1 (0.60) LPAR1LPAR3LPAR2LPAR5USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7811988-B2 Lipid mixtures for synthetic surfactants CHIESI FARMACEUTICI S.P.A. (IT) 2010-10-12 — — US claimed
EP-1628634-B1 NOVEL LIPID MIXTURES FOR SYNTHETIC SURFACTANTS CHIESI FARMA SPA (IT) 2009-12-23 — — EP claimed
US-20080045449-A1 A lipid mixture for synthetic surfactants comprising >40% by weight of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and >10% of polyunsaturated phospholipids; treatment of surfactant deficiencies like infant respiratory distress syndrome (RDS); rheology; low surface tension; fast spreading CHIESI FARMACEUTICI S.P.A. (IT) 2008-02-21 — — US claimed
EP-3727418-B1 SURFACTANT FORMULATIONS FOR INHALATION MERZ PHARMACEUTICALS LLC (US) 2026-04-08 — — EP disclosed
EP-3474832-B1 SURFACTANT FORMULATIONS FOR INHALATION MERZ PHARMACEUTICALS LLC (US) 2026-03-18 — — EP disclosed
US-20250288516-A1 Surfactant Formulations for Inhalation MERZ PHARMACEUTICALS LLC (US) 2025-09-18 — — US disclosed
US-20250262150-A1 Surfactant Formulations for Inhalation MERZ PHARMACEUTICALS LLC (US) 2025-08-21 — — US disclosed
US-20240016823-A1 SURFACTANT FORMULATIONS FOR INHALATION MERZ PHARMACEUTICALS, LLC 2024-01-18 — — US disclosed
CN-116355917-B Varicella-zoster virus mRNA vaccine and application thereof 上海臻上医药科技有限公司 2023-12-01 — — CN disclosed
CN-116747323-A Microneedle injection mRNA reagent with high drug loading rate and application thereof 上海臻上医药科技有限公司 2023-09-15 — — CN disclosed
CN-116355917-A Varicella-zoster virus mRNA vaccine and application thereof 上海臻上医药科技有限公司 2023-06-30 — — CN disclosed
US-7592469-B2 Lipid-analogous phosphoric acid triesters MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2009-09-22 — — US disclosed
US-20080045449-A1 A lipid mixture for synthetic surfactants comprising >40% by weight of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and >10% of polyunsaturated phospholipids; treatment of surfactant deficiencies like infant respiratory distress syndrome (RDS); rheology; low surface tension; fast spreading CHIESI FARMACEUTICI S.P.A. (IT) 2008-02-21 — — US disclosed
EP-0968206-B8 N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS BERLEX INC (US) 2007-01-24 — — EP disclosed
EP-1628634-A1 NOVEL LIPID MIXTURES FOR SYNTHETIC SURFACTANTS CHIESI FARMACEUTICI S.p.A. (IT) 2006-03-01 — — EP disclosed
US-20060039963-A1 Lipid-analogo phosphoric acid triesters MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2006-02-23 — — US disclosed
WO-2004105726-A1 NOVEL LIPID MIXTURES FOR SYNTHETIC SURFACTANTS CHIESI FARMACEUTICI S.P.A. (IT) 2004-12-09 — — WO disclosed
EP-1481665-A1 Novel lipid mixtures for synthetic surfactants CHIESI FARMACEUTICI S.p.A. (IT) 2004-12-01 — — EP disclosed
EP-0968206-A1 N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS BERLEX LABORATORIES, INC. (US) 2000-01-05 — — EP disclosed
WO-1998037079-A1 N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS BERLEX LABORATORIES, INC. (US) 1998-08-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060039963-A1 Lipid-analogo phosphoric acid triesters PHOSPHO1, LIPC, LIPA LPAR1 22/4885LPAR3 45/4885ALDH1A1 2689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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