SCHEMBL4428343

SCHEMBL4428343

CCCCC(c1c(Cl)cccc1Cl)c1c(Cl)cccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
DRD3 P35462 2/20 0.36
DRD2 P14416 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
OPRM1 P35372 5/20 0.35
OPRD1 P41143 5/20 0.35
OPRK1 P41145 5/20 0.35
OPRL1 P41146 5/20 0.35
HPGD P15428 1/20 0.35
CSNK1E P49674 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15786471 0.82 MEN1 (0.39) MEN1KMT2ANPSR1TP53CYP1A2
SCHEMBL18567612 0.80 MEN1 (0.40) MEN1KMT2ATP53CYP1A2CYP3A4
SCHEMBL18007012 0.80 MEN1 (0.35) MEN1KMT2ATP53CYP1A2CYP3A4
SCHEMBL20178499 0.79 MEN1 (0.43) MEN1KMT2ANPSR1TP53CYP1A2
SCHEMBL5614632 0.77 CYP2A13 (0.33) MEN1KMT2ANPSR1OPRM1OPRD1
SCHEMBL252530 0.77 MEN1 (0.39) MEN1KMT2ATP53CYP1A2CYP3A4
SCHEMBL253314 0.77 MEN1 (0.39) MEN1KMT2ATP53CYP1A2CYP3A4
SCHEMBL253315 0.77 MEN1 (0.39) MEN1KMT2ATP53CYP1A2CYP3A4
SCHEMBL7464415 0.77 MEN1 (0.39) MEN1KMT2ANPSR1TP53CYP1A2
SCHEMBL252988 0.77 MEN1 (0.39) MEN1KMT2ATP53CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105206732-B Flastic molding device and luminescent device 沙特基础全球技术有限公司 2018-11-09 CN disclosed
CN-105026459-B Cross-linked polycarbonate resin with improved chemical resistance and anti-flammability 沙特基础全球技术有限公司 2018-11-06 CN disclosed
CN-104884501-B Crosslinked polycarbonate resins with improved chemical and flame resistance 沙特基础全球技术有限公司 2018-06-29 CN disclosed
EP-2016113-A1 THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2009-01-21 EP disclosed
WO-2007108867-A1 THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2007-09-27 WO disclosed