Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428343 | 0.80 | MEN1 (0.40) | MEN1KMT2ACYP3A4TP53CYP1A2 | |
| SCHEMBL6685354 | 0.79 | NISCH (0.40) | MEN1KMT2ACYP3A4TSHRCYP2C19 | |
| SCHEMBL15786471 | 0.78 | MEN1 (0.39) | MEN1KMT2ACYP3A4TP53CYP1A2 | |
| SCHEMBL15698546 | 0.78 | CFD (0.47) | MEN1KMT2ACYP3A4CYP1A2DRD3 | |
| SCHEMBL18006937 | 0.77 | SMN1; SMN2 (0.34) | MEN1KMT2ACYP3A4DRD3DRD2 | |
| SCHEMBL18241990 | 0.76 | TAS1R3 (0.39) | MEN1KMT2ACYP3A4TP53CYP1A2 | |
| SCHEMBL5487851 | 0.76 | FFAR1 (0.37) | CYP3A4TDP1KCNH2LMNACA2 | |
| SCHEMBL252530 | 0.74 | MEN1 (0.39) | MEN1KMT2ACYP3A4TP53CYP1A2 | |
| SCHEMBL253314 | 0.74 | MEN1 (0.39) | MEN1KMT2ACYP3A4TP53CYP1A2 | |
| SCHEMBL252988 | 0.74 | MEN1 (0.39) | MEN1KMT2ACYP3A4TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016132134-A1 | THIAZOLE DERIVATIVES FOR THE TREATMENT OF ANIMAL TRYPANOSOMIASIS | UNIVERSITY OF DUNDEE (GB) | 2016-08-25 | — | — | WO | disclosed |