SCHEMBL4428476

SCHEMBL4428476

CO[Si](CCN(C)CC[Si](OC)(OC)OC)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPT P10636 1/20 0.32
LMNA P02545 2/20 0.31
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30
HBB P68871 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL329821 0.90 CA12 (0.52) CA12CA2CA3CA4CA6
SCHEMBL329627 0.90 CA12 (0.52) CA12CA2CA3CA4CA6
SCHEMBL20210402 0.88 MAPT (0.55) MAPTLMNATP53TSHRHTT
SCHEMBL329550 0.88 CA12 (0.32) CA12CA2CA3CA4CA6
SCHEMBL17515834 0.88 MAPT (0.36) MEN1KMT2AMAPT
SCHEMBL329553 0.86 CA12 (0.31) CA12CA2CA3CA4CA6
SCHEMBL495591 0.83 LMNA (0.38) CA12CA2CA3CA4CA6
SCHEMBL329587 0.82 ALDH1A1 (0.33) CA12CA2CA3CA4CA6
SCHEMBL16862734 0.81 CHRM2 (0.39) LMNA
SCHEMBL21924967 0.81 LMNA (0.36) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10072138-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD (JP) 2018-09-11 US disclosed
US-9567451-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-02-14 US disclosed
US-9493638-B2 Rubber composition for tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-11-15 US disclosed
US-9475924-B2 Rubber composition for tire tread and pneumatic tire using the same THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-10-25 US disclosed
US-9416252-B2 Rubber composition for tire tread THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-08-16 US disclosed
US-9139721-B2 Rubber composition for tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-09-22 US disclosed
US-20150126643-A1 Rubber Composition for Tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-05-07 US disclosed
US-20150031791-A1 Rubber Composition for Tire Treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-01-29 US disclosed
US-20130338255-A1 RUBBER COMPOSITION FOR TIRE TREAD THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-12-19 US disclosed
US-20130324638-A1 RUBBER COMPOSITION FOR USE IN TIRE TREADS THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-12-05 US disclosed
US-20130267646-A1 RUBBER COMPOSITION FOR TIRE TREAD AND PNEUMATIC TIRE USING THE SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-10-10 US disclosed
EP-2003146-B1 USE OF A CONJUGATED DIENE RUBBER FOR A TIRE ZEON CORP (JP) 2012-12-26 EP disclosed
EP-2003146-A9 CONJUGATED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION FOR TIRE, AND TIRE ZEON CORPORATION (JP) 2009-05-06 EP disclosed
EP-2003146-A2 CONJUGATED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION FOR TIRE, AND TIRE ZEON CORPORATION (JP) 2008-12-17 EP disclosed