Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 10/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 19/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652051 | 0.86 | NR3C2 (0.65) | NR3C2NR3C1PGR | |
| SCHEMBL3658305 | 0.83 | NR3C2 (0.49) | NR3C2NR3C1PGR | |
| SCHEMBL3652962 | 0.79 | NR3C1 (0.51) | NR3C2NR3C1PGR | |
| SCHEMBL3680388 | 0.79 | NR3C1 (0.56) | NR3C2NR3C1PGR | |
| SCHEMBL22023841 | 0.78 | NPSR1 (0.47) | NR3C2NR3C1 | |
| SCHEMBL17955454 | 0.75 | RBP4 (0.47) | NR3C2 | |
| SCHEMBL15759110 | 0.73 | NR3C1 (0.71) | NR3C2NR3C1PGR | |
| SCHEMBL5521382 | 0.73 | NR3C1 (0.57) | NR3C2NR3C1PGR | |
| SCHEMBL3954499 | 0.72 | NR3C2 (0.68) | NR3C2NR3C1PGR | |
| SCHEMBL3685002 | 0.72 | NR3C1 (0.49) | NR3C2NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2056799-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING GLAUCOMA OR PROGRESSION THEREOF | Bausch & Lomb Incorporated (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008027796-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING GLAUCOMA OR PROGRESSION THEREOF | BAUSCH & LOMB INCORPORATED (US) | 2008-03-06 | — | — | WO | disclosed |