SCHEMBL4428952

SCHEMBL4428952

CCC(CCCl)OC(CC)CCCl

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11796391 0.81 MAPK1 (0.30) MAPK1
SCHEMBL28542540 0.80 TSHR (0.32) TSHR
SCHEMBL9009391 0.79 TSHR (0.42) TSHR
SCHEMBL9009302 0.79 TSHR (0.42) TSHR
SCHEMBL7942723 0.76 TSHR (0.41) TSHR
SCHEMBL10625732 0.75 MAPK1 (0.40) TSHRMAPK1
SCHEMBL267594 0.75 PRKCA (0.34) TSHR
SCHEMBL246513 0.73 TSHR (0.41) TSHR
SCHEMBL19546012 0.73 PRKCA (0.33) TSHR
SCHEMBL14775448 0.73 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112390909-B preparation method and application of pH/salt double-sensitive ether-based functionalized polyion liquid gel 西安工程大学 2022-09-02 CN claimed
CN-112473396-B Anion exchange membrane material for diffusion dialysis acid recovery and preparation method thereof 西安建筑科技大学 2022-06-24 CN claimed
CN-112473396-A Anion exchange membrane material for diffusion dialysis acid recovery and preparation method thereof 西安建筑科技大学 2021-03-12 CN claimed
CN-112390909-A preparation method and application of pH/salt double-sensitive ether-based functionalized polyion liquid gel 西安工程大学 2021-02-23 CN claimed
EP-4736988-A1 ACIDIC GAS-ABSORBING LIQUID AND ACIDIC GAS REDUCTION METHOD AGC INC. (JP) 2026-05-06 EP disclosed
EP-4736989-A1 ACIDIC GAS-ABSORBING LIQUID AND ACIDIC GAS REDUCTION METHOD AGC INC. (JP) 2026-05-06 EP disclosed
US-20260115649-A1 ACIDIC GAS-ABSORBING LIQUID AND ACIDIC GAS REDUCTION METHOD AGC Inc. (JP) 2026-04-30 US disclosed
US-20260115646-A1 ACIDIC GAS-ABSORBING LIQUID AND ACIDIC GAS REDUCTION METHOD AGC Inc. (JP) 2026-04-30 US disclosed
CN-112390909-B preparation method and application of pH/salt double-sensitive ether-based functionalized polyion liquid gel 西安工程大学 2022-09-02 CN disclosed
CN-112473396-B Anion exchange membrane material for diffusion dialysis acid recovery and preparation method thereof 西安建筑科技大学 2022-06-24 CN disclosed
CN-112473396-A Anion exchange membrane material for diffusion dialysis acid recovery and preparation method thereof 西安建筑科技大学 2021-03-12 CN disclosed
CN-112390909-A preparation method and application of pH/salt double-sensitive ether-based functionalized polyion liquid gel 西安工程大学 2021-02-23 CN disclosed
US-6441000-B1 DISEASES MEDIATED BY OPIATE RECEPTORS PFIZER INC 2002-08-27 US disclosed
EP-1140896-A1 BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 Takeda Chemical Industries, Ltd. (JP) 2001-10-10 EP disclosed
US-6235771-B1 AIDS THERPAY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-05-22 US disclosed
EP-1055668-A1 New 4-arylpiperidine derivatives for the treatment of pruritus PFIZER INC. (US) 2000-11-29 EP disclosed
WO-2000037455-A1 BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-06-29 WO disclosed
US-5583227-A INHIBIT SECRETION OF GASTRIC ACID MOCHIDA PHARMACEUTICAL CO. LTD. (JP) 1996-12-10 US disclosed
EP-0685468-A1 Pyrazine and quinoxaline derivatives and their use as anti-ulcer agents Mochida Pharmaceutical Co., Ltd. (JP) 1995-12-06 EP disclosed
US-4000275-A BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES ELI LILLY AND COMPANY (US) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115646-A1 ACIDIC GAS-ABSORBING LIQUID AND ACIDIC GAS REDUCTION METHOD CA7, CA3, CA12 TSHR 4085/4885MAPK1 3393/4885
US-20260115649-A1 ACIDIC GAS-ABSORBING LIQUID AND ACIDIC GAS REDUCTION METHOD CA7, CA9, CA12 TSHR 4262/4885MAPK1 3244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.