Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 15/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436154 | 0.84 | KCNH2 (0.47) | KCNH2LMNAL3MBTL1 | |
| SCHEMBL4423521 | 0.83 | KCNH2 (0.69) | KCNH2 | |
| SCHEMBL4427594 | 0.82 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL4427774 | 0.81 | KCNH2 (0.67) | KCNH2 | |
| SCHEMBL4435540 | 0.79 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL4436261 | 0.78 | NCOA3 (0.50) | KCNH2 | |
| SCHEMBL4433626 | 0.77 | KCNH2 (0.60) | KCNH2 | |
| Hydrochloric Acid SCHEMBL7161630 | 0.77 | IDO1 (0.56) | IDO1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4433511 | 0.77 | IDO1 (0.56) | IDO1L3MBTL1 | |
| SCHEMBL4435791 | 0.77 | KCNH2 (0.51) | KCNH2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358165-B1 | IMIDAZOLE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-03-11 | — | — | EP | disclosed |