Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2423608 | 0.79 | LMNA (0.33) | MAPTLMNAKDM4EHTTPOLB | |
| SCHEMBL29871779 | 0.79 | MAPT (0.54) | MAPTLMNATP53KDM4ECCR1 | |
| SCHEMBL6847092 | 0.79 | MAPT (0.54) | MAPTLMNATP53KDM4ECCR1 | |
| SCHEMBL5454156 | 0.77 | MAPT (0.52) | MAPTLMNATP53KDM4ECCR1 | |
| SCHEMBL1982985 | 0.77 | CYP3A4 (0.47) | MAPTLMNAKDM4EHSP90AA1CYP3A4 | |
| SCHEMBL1287815 | 0.75 | MCL1 (0.46) | KDM4ETSHRCYP3A4HTTSMN1; SMN2 | |
| SCHEMBL29486398 | 0.74 | DAO (0.56) | — | |
| SCHEMBL747250 | 0.74 | DAO (0.56) | — | |
| SCHEMBL29486393 | 0.74 | DAO (0.56) | — | |
| SCHEMBL5514516 | 0.73 | MAPT (0.47) | MAPTLMNATP53KDM4ECCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009001544-A | PYRIDO[3,2-H]QUINAZOLINONES AND/OR 5,6-DIHYDRO DERIVATIVES THEREOF, METHOD FOR PRODUCING THE SAME AND DOPED ORGANIC SEMICONDUCTOR MATERIAL CONTAINING THE SAME | NOVALED AG | 2009-01-08 | — | — | JP | disclosed |
| EP-0944641-A1 | NON-HELICAL SUPRAMOLECULAR NANOSYSTEMS | Nanogen Recognomics GmbH (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025943-A1 | NON-HELICAL SUPRAMOLECULAR NANOSYSTEMS | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-06-18 | — | — | WO | disclosed |