Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213543 | 1.00 | KDM4E (0.46) | KDM4EMAPTGFERHTR2BPOLB | |
| SCHEMBL14192852 | 1.00 | KDM4E (0.46) | KDM4EMAPTGFERHTR2BPOLB | |
| Hydrochloric Acid SCHEMBL3215136 | 0.99 | KDM4E (0.48) | KDM4EMAPTGFERHTR2BPOLB | |
| SCHEMBL2674802 | 0.86 | HTR2B (0.55) | KDM4EMAPTGFERHTR2BPOLB | |
| SCHEMBL6756134 | 0.82 | NPC1 (0.59) | KDM4EMAPTGFERHTR2BPOLB | |
| SCHEMBL6756130 | 0.82 | NPC1 (0.47) | KDM4EHTR2BPOLBNPC1RAB9A | |
| SCHEMBL20677809 | 0.82 | ALDH1A1 (0.52) | KDM4EMAPTHTR2BPOLBNPC1 | |
| SCHEMBL724921 | 0.81 | NPC1 (0.62) | KDM4EMAPTGFERHTR2BPOLB | |
| SCHEMBL6757201 | 0.81 | NPC1 (0.62) | KDM4EMAPTGFERHTR2BPOLB | |
| SCHEMBL29466314 | 0.80 | NPC1 (0.51) | HTR2BPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121626-A1 | BENZIMIDAZOLE DERIVATIVES | Pfizer Products Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008075196-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-06-26 | — | — | WO | disclosed |