SCHEMBL4429618

SCHEMBL4429618

CCC(=O)Nc1ccc2nc(NC(=O)CC)ccc2c1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.52
RAB9A P51151 7/20 0.51
NPC1 O15118 4/20 0.51
KDM4E B2RXH2 2/20 0.51
TERT O14746 2/20 0.50
CYP3A4 P08684 2/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
RORC P51449 1/20 0.47
TSHR P16473 1/20 0.47
POLB P06746 3/20 0.46
NR4A1 P22736 1/20 0.46
PLAU P00749 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HPGD P15428 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8901234 0.90 CYP3A4 (0.50) MCHR1RAB9ANPC1KDM4ETERT
SCHEMBL14157781 0.82 CYP3A4 (0.65) RAB9ANPC1KDM4ECYP3A4MEN1
SCHEMBL4413382 0.80 NPC1 (0.64) RAB9ANPC1KMT2A
SCHEMBL8402849 0.78 NPC1 (0.70) RAB9ANPC1KDM4ECYP3A4MEN1
SCHEMBL9881015 0.77 RAB9A (0.56) MCHR1RAB9ANPC1KDM4ETERT
SCHEMBL31152634 0.76 ALDH1A1 (0.73) RAB9ANPC1KDM4ECYP3A4MEN1
SCHEMBL1285643 0.76 ALDH1A1 (0.73) RAB9ANPC1KDM4ECYP3A4MEN1
SCHEMBL21765699 0.76 RAB9A (0.72) RAB9ANPC1KDM4ECYP3A4MEN1
SCHEMBL19706518 0.74 NOTUM (0.63) RAB9ANPC1KDM4ECYP3A4MEN1
SCHEMBL27936888 0.74 AR (0.62) RAB9ANPC1KDM4ECYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed