SCHEMBL4429629

SCHEMBL4429629

O=C1CC(c2cccc(Cl)c2Cl)C(=O)N1

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 11/20 0.58
TSHR P16473 1/20 0.58
ALDH1A1 P00352 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
LMNA P02545 1/20 0.48
CYP19A1 P11511 1/20 0.44
TP53 P04637 1/20 0.43
PGR P06401 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5323542 0.86 IDO1 (0.61) IDO1ALDH1A1LMNA
SCHEMBL11374966 0.79 IDO1 (0.50) IDO1TSHRALDH1A1LMNACYP19A1
SCHEMBL880437 0.76 LMNA (0.61) IDO1TSHRALDH1A1TDP1LMNA
SCHEMBL14450608 0.76 LMNA (0.61) IDO1TSHRALDH1A1TDP1LMNA
SCHEMBL8155584 0.75 IDO1 (0.62) IDO1LMNACYP19A1TP53
SCHEMBL9387969 0.73 IDO1 (1.00) IDO1LMNACYP19A1TP53
SCHEMBL5814880 0.73 IDO1 (0.58) IDO1ALDH1A1LMNACYP19A1TP53
SCHEMBL17258070 0.73 IDO1 (0.71) IDO1LMNATP53
SCHEMBL17258053 0.73 IDO1 (0.71) IDO1ALDH1A1LMNATP53
SCHEMBL6918058 0.72 IDO1 (0.61) IDO1ALDH1A1LMNACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110290705-A Fungicidal compounds and mixtures for fungicidal control in cereals 美国陶氏益农公司 2019-09-27 CN disclosed
CN-106061259-B Synergistic fungicidal mixture for fungus control in cereal 美国陶氏益农公司 2019-08-16 CN disclosed
US-10362787-B2 Method for propagating microorganisms within plant bioreactors and stably storing microorganisms within agricultural seeds AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH (AT) 2019-07-30 US disclosed
CN-109996443-A The purposes of two fluoro- fungicides of (2- hydroxypropyl) pyridine compounds as the plant pathogenic fungi for preventing and treating wheat 美国陶氏益农公司 2019-07-09 CN disclosed
CN-109863148-A The purposes of fungicide prevention and treatment pomaceous fruit and the brown rot on tone fruit trees before UK-2A 美国陶氏益农公司 2019-06-07 CN disclosed
CN-109843063-A Pyrido-1, 3-oxazin-2, 4-dione compounds with fungicidal activity 美国陶氏益农公司 2019-06-04 CN disclosed
CN-109843877-A The purposes of fungicide prevention and treatment rice blast before UK-2A 美国陶氏益农公司 2019-06-04 CN disclosed
CN-109843057-A Pyridine amide N-oxide compounds having fungicidal activity 美国陶氏益农公司 2019-06-04 CN disclosed
CN-109843060-A Pyridine amide N-oxide compounds having fungicidal activity 美国陶氏益农公司 2019-06-04 CN disclosed
CN-109843058-A PICOLINAMIDES AS FUNGICIDES 美国陶氏益农公司 2019-06-04 CN disclosed
CN-106061260-A Synergistic fungicidal mixtures for fungal control in cereals 美国陶氏益农公司 2016-10-26 CN disclosed
CN-106061263-A Synergistic fungicidal mixtures for controlling fungi in cereals 阿达玛马克西姆股份有限公司 2016-10-26 CN disclosed
CN-106061259-A Synergistic fungicidal mixtures for fungal control in cereals 美国陶氏益农公司 2016-10-26 CN disclosed
CN-106061262-A Synergistic fungicidal mixtures for controlling fungi in cereals 阿达玛马克西姆股份有限公司 2016-10-26 CN disclosed
CN-106028814-A Use of macrocyclic picolinamides as fungicides 美国陶氏益农公司 2016-10-12 CN disclosed
CN-106028815-A Macrocyclic picolinamides as fungicides 美国陶氏益农公司 2016-10-12 CN disclosed
WO-2015161095-A1 METHODS OF USEING TANKMIX ADDITIVE CONCENTRATES CONTAINING PARAFFINIC OILS DOW AGROSCIENCES LLC (US) 2015-10-22 WO disclosed
EP-2057120-A1 INSECTICIDAL N-SUBSTITUTED (HETEROARYL)CYCLOALKYL SULFOXIMINES Dow AgroSciences LLC (US) 2009-05-13 EP disclosed
WO-2008027073-A1 INSECTICIDAL N-SUBSTITUTED (HETEROARYL)CYCLOALKYL SULFOXIMINES DOW AGROSCIENCES LLC (US) 2008-03-06 WO disclosed
WO-2006034342-A2 CONTROLLED RELEASE FERTILIZERS CONTAINING CALCIUM SULFATE AND PROCESSES FOR MAKING SAME NFT INDUSTRIES, LLC (US) 2006-03-30 WO disclosed