Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 5/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436861 | 0.84 | NPC1 (0.42) | ALDH1A1KDM4ELMNASMN1; SMN2MEN1 | |
| SCHEMBL4608554 | 0.81 | PTPRC (0.49) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4426244 | 0.80 | PTGDR2 (0.41) | CTSAPTGDR2MAPTNPSR1L3MBTL1 | |
| SCHEMBL4429993 | 0.79 | S1PR4 (0.38) | ALDH1A1KDM4ESMN1; SMN2BACE1MAOB | |
| SCHEMBL14003492 | 0.77 | ACHE (0.65) | ACHEALDH1A1CYP3A4KDM4ESMN1; SMN2 | |
| SCHEMBL14446041 | 0.76 | ACHE (0.58) | ACHEALDH1A1CYP3A4KDM4ELMNA | |
| SCHEMBL4431126 | 0.76 | ALKBH3 (0.37) | — | |
| SCHEMBL4433441 | 0.76 | MAOB (0.31) | MAOBMAOA | |
| SCHEMBL4429890 | 0.76 | ACHE (0.48) | ACHEALDH1A1CYP3A4KDM4ELMNA | |
| SCHEMBL26698533 | 0.75 | KCNH2 (0.43) | CYP3A4SYKCTSACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |