SCHEMBL4433441

SCHEMBL4433441

Cc1[c]ccc(-c2cc(C)ccc2Br)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.31
MAOA P21397 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4437746 0.86 S100A4 (0.35)
SCHEMBL4429993 0.81 S1PR4 (0.38) MAOBMAOA
SCHEMBL4438085 0.79 NOTUM (0.33)
SCHEMBL4431126 0.79 ALKBH3 (0.37)
SCHEMBL4429707 0.76 ACHE (0.46) MAOBMAOA
SCHEMBL4432034 0.74 MAOB (0.36) MAOBMAOA
SCHEMBL7795311 0.74
SCHEMBL5199467 0.74 S100A4 (0.30)
SCHEMBL1939273 0.73 ALDH1A1 (0.31)
SCHEMBL13407668 0.73 ALDH1A1 (0.43) MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121660-A2 FUNGICIDAL AMIDES E. I. Du Pont de Nemours and Company (US) 2009-11-25 EP disclosed
WO-2008091580-A2 FUNGICIDAL AMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-31 WO disclosed
EP-1948649-A2 FUNGICIDAL CARBOXAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-30 EP disclosed
WO-2007014290-A2 FUNGICIDAL CARBOXAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-01 WO disclosed