SCHEMBL4429926

SCHEMBL4429926

O=C=NCCC(Cl)CC(=O)O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.32
FOLH1 Q04609 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7872222 0.76
SCHEMBL482964 0.74
SCHEMBL12492498 0.72 GSTK1 (0.37) SLC22A6
SCHEMBL1262446 0.71 SLC22A6 (0.50) SLC22A6FOLH1TDP1SMN1; SMN2
SCHEMBL12491035 0.71 GSTK1 (0.35) SLC22A6FOLH1TDP1SMN1; SMN2
SCHEMBL28654356 0.71 FOLH1 (0.40) FOLH1
SCHEMBL4420749 0.71
SCHEMBL4284728 0.70
SCHEMBL9620654 0.70 GPR84 (0.45) SLC22A6FOLH1TDP1SMN1; SMN2
SCHEMBL11762978 0.70 FOLH1 (0.52) SLC22A6FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7632965-B2 Method for producing (meth)acrylate derivative having isocyanate group SHOWA DENKO K.K. (JP) 2009-12-15 US disclosed
US-20070197762-A1 Method For Producing (Meth)Acrylate Derivative Having Isocyanate Group SHOWA DENKO K.K. (JP) 2007-08-23 US disclosed