Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12342743 | 0.85 | CA12 (0.32) | ALDH1A1CA1 | |
| SCHEMBL12450552 | 0.71 | LMNA (0.39) | LMNATDP1ALDH1A1FFAR3SOAT1 | |
| SCHEMBL6244448 | 0.65 | — | — | |
| SCHEMBL10397253 | 0.65 | ALDH1A1 (0.39) | LMNATDP1ALDH1A1FFAR3SOAT1 | |
| SCHEMBL139066 | 0.65 | — | — | |
| SCHEMBL28294414 | 0.65 | CA1 (0.33) | LMNACA1 | |
| SCHEMBL1756719 | 0.65 | FFAR3 (0.33) | LMNAALDH1A1FFAR3 | |
| SCHEMBL17375318 | 0.65 | TDP1 (0.33) | TDP1ALDH1A1FFAR3SOAT1 | |
| SCHEMBL28629077 | 0.64 | ALDH1A1 (0.44) | LMNATDP1ALDH1A1FFAR3SOAT1 | |
| SCHEMBL24636824 | 0.63 | ALDH1A1 (0.37) | TDP1ALDH1A1FFAR3CA1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064385-B1 | ENZYMATIC TREATMENT OF TEXTILES USING A PECTATE LYASE FROM BACILLUS SUBTILIS | DANISCO US INC GENENCOR DIV (US) | 2016-02-17 | — | — | EP | disclosed |
| US-8420659-B2 | Compositions and methods for inhibition of the JAK pathway | RIGEL PHARMACEUTICALS, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20120301486-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | Riger Pharmaceuticals, Inc. | 2012-11-29 | — | — | US | disclosed |
| US-8268851-B2 | Compositions and methods for inhibition of the JAK pathway | RIGEL PHARMACEUTICALS, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20100158921-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | RIGEL PHARMACEUTICALS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| EP-2064385-A2 | ENZYMATIC TREATMENT OF TEXTILES USING A PECTATE LYASE FROM BACILLUS SUBTILIS | Danisco US, INC., Genencor Division (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008039353-A2 | ENZYMATIC TREATMENT OF TEXTILES USING A PECTATE LYASE FROM BACILLUS SUBTILIS | DANISCO US, INC., GENENCOR DIVISION (US) | 2008-04-03 | — | — | WO | disclosed |
| US-20060042020-A1 | Treatment of fabrics, fibers, or yarns | NOVOZYMES NORTH AMERICA, INC. (US) | 2006-03-02 | — | — | US | disclosed |
| US-6777530-B1 | CROSSLINKED OLIGO- AND POLYAMINES AS SOIL RELEASE AGENTS AND ENZYME STABILIZERS IN DETERGENTS AND CLEANERS | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-17 | — | — | US | disclosed |
| EP-1404798-A4 | PREPARATION OF CELLULOSIC MATERIALS | NOVOZYMES NORTH AMERICA INC (US) | 2004-08-04 | — | — | EP | disclosed |
| US-20020013245-A1 | SOLID COMPOSITION CONSISTING OF HETEROCYCLIC COMPOUNDS AND/ OR OXIME ESTERS AND INERT POROUS CARRIER MATERIALS AND THE USE THEREOF AS STABLE BLEACH ACTIVATOR COMPONENT IN DETERGENTS, BLEACHES AND CLEANERS | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-31 | — | — | US | disclosed |
| US-6331519-B1 | MIXING POLYETHYLENIMINE FORMED BY PARTIAL HYDROLYSIS OF OLIGO/POLYVINYLFORMAMIDES WITH DI- OR POLYCARBOXYLIC ACID OR SALT; COLOR TEXTILES, COTTON | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-18 | — | — | US | disclosed |
| US-6300305-B1 | BOOSTING DETERGENTS BY MIXING WITH AMINES FOR FABRICS | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-09 | — | — | US | disclosed |
| US-6258295-B1 | ACTIVATING INORGANIC PEROXY COMPOUNDS BY CONTACTING WITH OXMINE ESTER COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | disclosed |
| US-6180590-B1 | USE OF A CYCLOPOLYAMINE AS DETERGENCY BOOSTER, PREFERABLY IN TEXTILE DETERGENTS, ESPECIALLY IN COLOR DETERGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-30 | — | — | US | disclosed |
| US-6130198-A | Bleaching efficiency boosters for bleach and textile detergent compositions | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-10 | — | — | US | disclosed |
| US-6083898-A | Water-soluble or water-dispersible cross-linked nitrogenated compounds in washing and cleaning agents | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-04 | — | — | US | disclosed |
| US-5994290-A | MIXTURES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-30 | — | — | US | disclosed |
| US-5972237-A | USED AS COLD BLEACH ACTIVATORS OR OPTICAL BRIGHTENERS IN DETERGENTS, CLEANERS AND BLEACHES AND IN DISINFECTANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-26 | — | — | US | disclosed |
| US-5733342-A | BUILDERS AND BLEACH STABILIZERS IN DETERGENTS AND CLEANING COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158921-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | JAK3, JAK2, JAK1 | LMNA 4322/4885TDP1 3292/4885ALDH1A1 4036/4885 |
| US-20120301486-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | JAK3, JAK2, JAK1 | LMNA 4322/4885TDP1 3292/4885ALDH1A1 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.