Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.47 |
| ▸ | UBE2M | P61081 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2388839 | 0.91 | DRD4 (0.68) | DRD4SIGMAR1POLBUTS2RSLC6A5 | |
| SCHEMBL4441069 | 0.87 | UTS2R (0.61) | SIGMAR1POLBUTS2RKMT2AMCHR1 | |
| SCHEMBL2390049 | 0.84 | DRD4 (0.67) | DRD4SIGMAR1POLBUTS2RSLC6A5 | |
| SCHEMBL2389006 | 0.83 | DRD4 (0.68) | DRD4SIGMAR1UTS2RSLC6A5KMT2A | |
| SCHEMBL2390109 | 0.82 | POLB (0.56) | DRD4SIGMAR1POLBUTS2RKMT2A | |
| SCHEMBL4435309 | 0.82 | POLB (0.61) | DRD4SIGMAR1POLBUTS2RKMT2A | |
| SCHEMBL2388674 | 0.81 | DRD4 (0.59) | DRD4SIGMAR1POLBUTS2RSLC6A5 | |
| SCHEMBL3668600 | 0.80 | DRD4 (0.52) | DRD4SIGMAR1SLC6A5MCHR1UBE2M | |
| SCHEMBL4429895 | 0.80 | UTS2R (0.65) | SIGMAR1POLBUTS2RKMT2AMCHR1 | |
| SCHEMBL4441461 | 0.80 | KMT2A (0.64) | DRD4SIGMAR1KMT2AMCHR1SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079694-A1 | N-SUBSTITUTED-HETEROCYCLOALKYLOXYBENZAMIDE COMPOUNDS AND METHODS OF USE | Rigel Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | claimed |
| WO-2008083124-A1 | N-SUBSTITUTED-HETEROCYCLOALKYLOXYBENZAMIDE COMPOUNDS AND METHODS OF USE | RIGEL PHARMACEUTICALS, INC. (US) | 2008-07-10 | — | — | WO | claimed |