SCHEMBL443070

SCHEMBL443070

COc1ccc2cc(OC)ccc2c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.79
CYP2A6 P11509 2/20 0.79
HSD17B1 P14061 1/20 0.65
HSD17B2 P37059 1/20 0.65
CA12 O43570 2/20 0.62
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
CA7 P43166 2/20 0.62
CA9 Q16790 2/20 0.62
CA14 Q9ULX7 2/20 0.62
KDM4E B2RXH2 1/20 0.60
GSTP1 P09211 1/20 0.60
NCF1 P14598 1/20 0.58
MEN1 O00255 1/20 0.56
POLB P06746 1/20 0.56
MAPK1 P28482 1/20 0.56
KMT2A Q03164 1/20 0.56
RAB9A P51151 2/20 0.56
CYP1A1 P04798 1/20 0.54
CYP1B1 Q16678 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29447161 1.00 CYP1A2 (0.79) CYP1A2CYP2A6HSD17B1HSD17B2CA12
SCHEMBL7451812 0.94 CYP1A2 (0.71) CYP1A2CYP2A6HSD17B1HSD17B2CA12
SCHEMBL7456084 0.94 CYP1A2 (0.71) CYP1A2CYP2A6HSD17B1HSD17B2CA12
SCHEMBL29367032 0.94 CYP2A6 (0.80) CYP1A2CYP2A6HSD17B1HSD17B2CA12
SCHEMBL2249185 0.94 CYP1A2 (0.71) CYP1A2CYP2A6HSD17B1HSD17B2CA12
SCHEMBL7452675 0.94 CYP1A2 (0.71) CYP1A2CYP2A6HSD17B1HSD17B2CA12
SCHEMBL6891918 0.94 CYP1A2 (0.71) CYP1A2CYP2A6HSD17B1HSD17B2CA12
SCHEMBL29919511 0.94 CYP1A2 (0.71) CYP1A2CYP2A6HSD17B1HSD17B2CA12
SCHEMBL443528 0.94 CYP2A6 (0.80) CYP1A2CYP2A6HSD17B1HSD17B2CA12
SCHEMBL22106286 0.91 CYP2A6 (0.68) CYP1A2CYP2A6HSD17B1HSD17B2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041669-B Epoxy resin monomer and preparation method and application thereof 中国建筑材料科学研究总院有限公司 2024-07-02 CN claimed
CN-116925102-A Multi-nitrogen bridged compound and preparation method thereof 北京理工大学 2023-10-24 CN claimed
CN-116041669-A Epoxy resin monomer and preparation method and application thereof 中国建筑材料科学研究总院有限公司 2023-05-02 CN claimed
CN-115340818-A High-performance high-temperature-resistant impregnating resin and preparation method thereof 丹阳市沃德立电工材料有限公司 2022-11-15 CN claimed
CN-111808048-A Preparation method of environment-friendly high-temperature-resistant epoxy impregnating resin 绍兴柯桥拟泰科技有限公司 2020-10-23 CN claimed
CN-110746575-A Preparation method of environment-friendly high-temperature-resistant epoxy impregnating resin 浙江荣泰科技企业有限公司 2020-02-04 CN claimed
EP-3081562-A1 COMPOUND FOR INHIBITING ACTIVITY OF GLUTATHIONE S-TRANSFERASE OMEGA 1 AND PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUND China Medical University (TW) 2016-10-19 EP claimed
CN-102757321-B Production method of 2,6-dimethoxynaphthalene NANTONG BAISHENG CHEMICAL CO LTD 2015-06-17 CN claimed
CN-103980245-A Compound for inhibiting glutathione S-transferase omega1 activity, preparation method thereof and pharmaceutical composition containing compound UNIV CHINA MEDICAL 2014-08-13 CN claimed
US-20140221470-A1 COMPOUND FOR INHIBITING GLUTATHIONE S-TRANSFERASE OMEGA 1 ACTIVITY, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF, AND METHOD FOR SYNTHESIZING THE SAME CHINA MEDICAL UNIVERSITY (TW) 2014-08-07 US claimed
WO-1994017985-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1994-08-18 WO claimed
EP-0606198-A1 MICROPOROUS HOLLOW FIBER OR FILM MEMBRANE OF POLY(PHENYLENE SULFIDE) (PPS) THE DOW CHEMICAL COMPANY (US) 1994-07-20 EP claimed
US-5266723-A Process for the preparation of optically active 2-aryl-alkanoic acids, especially 2-aryl-propionic acids MEDICE, LTD., CHEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) 1993-11-30 US claimed
US-5246647-A Solvent THE DOW CHEMICAL COMPANY (US) 1993-09-21 US claimed
US-5227101-A Blending, heating, extruding or casting, quenching or coagulating and leaching a blend of unsulfonated polyether ketone copolymers and partially imcompatible polymer THE DOW CHEMICAL COMPANY (US) 1993-07-13 US claimed
US-5205968-A Process for making a microporous membrane from a blend containing a poly(etheretherketone)-type polymer, an amorphous polymer, and a solvent THE DOW CHEMICAL COMPANY (US) 1993-04-27 US claimed
WO-1993004223-A1 MICROPOROUS HOLLOW FIBER OR FILM MEMBRANE OF POLY(PHENYLENE SULFIDE) (PPS) THE DOW CHEMICAL COMPANY (US) 1993-03-04 WO claimed
US-5064580-A Heating, extrusion, coagulation, leaching out of plasticizer THE DOW CHEMICAL COMPANY (US) 1991-11-12 US claimed
US-5043112-A Dissolving polyphenylene sulfide in hot melted high-boiling boiling organic solvent, shaping, desolventizing, cooling THE DOW CHEMICAL COMPANY (US) 1991-08-27 US claimed
US-4904426-A MOCROPOROUS; AROMATIC RING-CONTAINING SOLVENT; EXTRUSION, QUENCHING, LEACHING, DRYING THE DOW CHEMICAL COMPANY (US) 1990-02-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140221470-A1 COMPOUND FOR INHIBITING GLUTATHIONE S-TRANSFERASE OMEGA 1 ACTIVITY, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF, AND METHOD FOR SYNTHESIZING THE SAME GSTO1, GSTA1, GSTP1 CYP1A2 191/4885CYP2A6 272/4885HSD17B1 271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.