SCHEMBL4430711

SCHEMBL4430711

OC(c1ccsc1)c1sccc1Br

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 2/20 0.33
ALOX5 P09917 1/20 0.33
IDO1 P14902 2/20 0.32
TDO2 P48775 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19219824 0.83 ADRA1D (0.38) ADRA1D
SCHEMBL5104539 0.76 ALOX5 (0.42) ALOX5IDO1TDO2
SCHEMBL5518330 0.72 CFTR (0.36) ALOX5IDO1TDO2
SCHEMBL10903974 0.71 IDO1 (0.38) ALOX5IDO1TDO2
SCHEMBL8632334 0.71 ALOX5 (0.33) ALOX5IDO1TDO2
SCHEMBL155103 0.71 TSHR (0.37) ADRA1DIDO1TDO2
SCHEMBL18003233 0.69
SCHEMBL2729342 0.68 ALOX5 (0.35) ALOX5IDO1TDO2
SCHEMBL18330012 0.68 ALOX5 (0.33) ALOX5IDO1TDO2
SCHEMBL27757242 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2828904-B1 CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES RAYNERGY TEK INC (TW) 2019-06-12 EP disclosed
EP-2828903-B1 OPTOELECTRONIC DEVICES COMPRISING POLYMERIC BLENDS RAYNERGY TEK INC (TW) 2017-11-01 EP disclosed
US-9312492-B2 Polymeric blends and related optoelectronic devices RAYNERGY TEK INC. (TW) 2016-04-12 US disclosed
US-20160072070-A1 POLYMERIC BLENDS AND RELATED OPTOELECTRONIC DEVICES POLYERA CORPORATION 2016-03-10 US disclosed
US-20160072070-A1 POLYMERIC BLENDS AND RELATED OPTOELECTRONIC DEVICES POLYERA CORPORATION 2016-03-10 US disclosed
US-20150171332-A1 POLYMERIC BLENDS AND RELATED OPTOELECTRONIC DEVICES RAYNERGY TEK INC. (TW) 2015-06-18 US disclosed
US-8883958-B2 Conjugated polymers and their use in optoelectronic devices RAYNERGY TEK INC. (TW) 2014-11-11 US disclosed
US-8883958-B2 Conjugated polymers and their use in optoelectronic devices RAYNERGY TEK INC. (TW) 2014-11-11 US disclosed
US-8841409-B2 Conjugated polymers and their use in optoelectronic devices POLYERA CORPORATION (US) 2014-09-23 US disclosed
US-8841409-B2 Conjugated polymers and their use in optoelectronic devices POLYERA CORPORATION (US) 2014-09-23 US disclosed
US-7468080-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2008-12-23 US disclosed
US-20080134450-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof WELLA OPERATIONS US, LLC 2008-06-12 US disclosed
US-20080134450-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof WELLA OPERATIONS US, LLC 2008-06-12 US disclosed
US-20080134450-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof WELLA OPERATIONS US, LLC 2008-06-12 US disclosed
US-7351266-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2008-04-01 US disclosed
US-7351266-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2008-04-01 US disclosed
US-7351266-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2008-04-01 US disclosed
EP-1720615-A1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2006-11-15 EP disclosed
WO-2005087187-A1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-09-22 WO disclosed
US-20050193504-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050193504-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof KRT18, CKMT1A; CKMT1B, KRTCAP2 ADRA1D 4408/4885ALOX5 662/4885IDO1 2690/4885
US-20080134450-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof KRT18, CKMT1A; CKMT1B, KRTCAP2 ADRA1D 4408/4885ALOX5 662/4885IDO1 2690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.