SCHEMBL4430724

SCHEMBL4430724

CCCN(C(=O)C1(O)CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC[C@H]([C@H](C)CCCC(C)C)[C@@]4(C)CC[C@@H]32)C1)N(C)C

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 2/20 0.60
▸ CYP46A1 Q9Y6A2 2/20 0.60
▸ LMNA P02545 1/20 0.60
▸ ABCB1 P08183 1/20 0.60
▸ OSBP P22059 1/20 0.60
▸ RORC P51449 1/20 0.60
▸ OSBP2 Q969R2 1/20 0.60
▸ POLA1 P09884 1/20 0.57
▸ GRIN1 Q05586 13/20 0.56
▸ GRIN2B Q13224 13/20 0.56
▸ GRIN2A Q12879 11/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL743933 0.94 USP2 (0.61) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL8159169 0.91 OSBP (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL6816995 0.88 USP2 (0.57) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL12274582 0.88 USP2 (0.61) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL565022 0.88 USP2 (0.58) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL3971279 0.88 USP2 (0.58) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2638134 0.87 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27975861 0.87 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL6060845 0.87 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27963054 0.87 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3100719-A2 DELIVERY OF NUCLEIC ACID-LIKE COMPOUNDS California Pacific Medical Center (US) 2016-12-07 — — EP disclosed
EP-1509203-B1 DELIVERY OF NUCLEIC ACID-LIKE COMPOUNDS CALIFORNIA PACIFIC MED CENTER (US) 2016-04-13 — — EP disclosed
US-20150140069-A1 DELIVERY OF NUCLEIC ACID-LIKE COMPOUNDS SUTTER WEST BAY HOSPITAL DBA CALIFORNIA PACIFIC MEDICAL CT (US) 2015-05-21 — — US disclosed
US-8883200-B2 Delivery of nucleic acid-like compounds SUTTER WEST BAY HOSPITALS (US) 2014-11-11 — — US disclosed
US-20140017300-A1 DELIVERY OF NUCLEIC ACID-LIKE COMPOUNDS Sutter West bay Hospital, DBA California Pacific Medical Center (US) 2014-01-16 — — US disclosed
US-8496961-B2 Delivery of nucleic acid-like compounds Sutter West Bay Hospital (US) 2013-07-30 — — US disclosed
US-20090171077-A1 DELIVERY OF NUCLEIC ACID-LIKE COMPOUNDS CALIFORNIA PACIFIC MEDICAL CENTER 2009-07-02 — — US disclosed
EP-1509203-A2 DELIVERY OF NUCLEIC ACID-LIKE COMPOUNDS California Pacific Medical Center (US) 2005-03-02 — — EP disclosed
US-20040037874-A1 Forming microparticulate complex that comprises particle forming component complexed to a nucleic acid-like component forming a spherical particle; drug delivery SUTTER WEST BAY HOSPITALS, DBA CALIFORNIA PACIFIC MEDICAL CENTER 2004-02-26 — — US disclosed
WO-2003097805-A2 DELIVERY OF NUCLEIC ACID-LIKE COMPOUNDS CALIFORNIA PACIFIC MEDICAL CENTER (US) 2003-11-27 — — WO disclosed
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