Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.68 |
| ▸ | OSBP | P22059 | 1/20 | 0.68 |
| ▸ | RORC | P51449 | 1/20 | 0.68 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.68 |
| ▸ | POLA1 | P09884 | 1/20 | 0.66 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 9/20 | 0.61 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.58 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975861 | 1.00 | USP2 (0.68) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL6060845 | 0.93 | USP2 (0.68) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL27963054 | 0.93 | USP2 (0.68) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL27963051 | 0.93 | USP2 (0.68) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL2221515 | 0.92 | USP2 (0.67) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL8426935 | 0.92 | USP2 (0.67) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL2637585 | 0.92 | USP2 (0.67) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL318120 | 0.90 | USP2 (0.65) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL8159169 | 0.90 | OSBP (0.65) | USP2CYP46A1LMNAABCB1OSBP | |
| SCHEMBL22194041 | 0.90 | USP2 (0.65) | USP2CYP46A1LMNAABCB1OSBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780031-B1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING GLUCOCORTICOID RECEPTOR ACTIVITY | UNIV INDIANA RES & TECH CORP (US) | 2018-03-07 | — | — | EP | disclosed |
| US-9783592-B2 | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-10-10 | — | — | US | disclosed |
| EP-2569000-B1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING NUCLEAR HORMONE RECEPTOR ACTIVITY | UNIV INDIANA RES & TECH CORP (US) | 2017-09-27 | — | — | EP | disclosed |
| CN-103079587-B | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORP. (US) | 2016-05-11 | — | — | CN | disclosed |
| US-20150320871-A1 | Glucagon Superfamily Peptides Exhibiting Nuclear Hormone Receptor Activity | UNIV INDIANA RES & TECH CORP (US) | 2015-11-12 | — | — | US | disclosed |
| US-9127088-B2 | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-09-08 | — | — | US | disclosed |
| US-8859491-B2 | Glucagon superfamily peptides exhibiting glucocorticoid receptor activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2014-10-14 | — | — | US | disclosed |
| EP-2780031-A1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING GLUCOCORTICOID RECEPTOR ACTIVITY | Indiana University Research and Technology Corporation (US) | 2014-09-24 | — | — | EP | disclosed |
| US-20130157934-A1 | Glucagon Superfamily Peptides Exhibiting Glucocorticoid Receptor Activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2013074910-A1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING GLUCOCORTICOID RECEPTOR ACTIVITY | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-05-23 | — | — | WO | disclosed |
| US-20130123178-A1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING NUCLEAR HORMONE RECEPTOR ACTIVITY | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-05-16 | — | — | US | disclosed |
| CN-103079587-A | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity | UNIV INDIANA RES & TECH CORP | 2013-05-01 | — | — | CN | disclosed |
| EP-2569000-A1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING NUCLEAR HORMONE RECEPTOR ACTIVITY | Indiana University Research and Technology Corporation (US) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011143209-A1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING NUCLEAR HORMONE RECEPTOR ACTIVITY | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2011-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150320871-A1 | Glucagon Superfamily Peptides Exhibiting Nuclear Hormone Receptor Activity | GIPR, GLP1R, GCGR | USP2 2542/4885CYP46A1 282/4885LMNA 3486/4885 |
| US-20130157934-A1 | Glucagon Superfamily Peptides Exhibiting Glucocorticoid Receptor Activity | GCGR, GIPR, GLP1R | USP2 2387/4885CYP46A1 343/4885LMNA 4397/4885 |
| US-20130123178-A1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING NUCLEAR HORMONE RECEPTOR ACTIVITY | GIPR, GLP1R, GCGR | USP2 2542/4885CYP46A1 282/4885LMNA 3486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.