SCHEMBL743933

SCHEMBL743933

CCN(C(=O)C1(O)CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC[C@H]([C@H](C)CCCC(C)C)[C@@]4(C)CC[C@@H]32)C1)N(C)C

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 2/20 0.61
▸ CYP46A1 Q9Y6A2 2/20 0.61
▸ LMNA P02545 1/20 0.61
▸ ABCB1 P08183 1/20 0.61
▸ OSBP P22059 1/20 0.61
▸ RORC P51449 1/20 0.61
▸ OSBP2 Q969R2 1/20 0.61
▸ POLA1 P09884 1/20 0.58
▸ GRIN1 Q05586 13/20 0.56
▸ GRIN2B Q13224 13/20 0.56
▸ GRIN2A Q12879 11/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4430724 0.94 USP2 (0.60) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL6816995 0.92 USP2 (0.57) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL8159169 0.92 OSBP (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL12274582 0.90 USP2 (0.61) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27963051 0.87 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27963054 0.87 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2638134 0.87 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27975861 0.87 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL6060845 0.87 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL565022 0.87 USP2 (0.58) USP2CYP46A1LMNAABCB1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118234486-A Uric acid liposome 巴塞罗纳医院门诊部 2024-06-21 — — CN claimed
CN-115957382-A Medical instrument for interventional therapy 凯诺威医疗科技(武汉)有限公司 2023-04-14 — — CN claimed
US-10098987-B2 Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs M.A. Med Alliance SA (CH) 2018-10-16 — — US claimed
US-9895313-B2 Combination liposomal pharmaceutical formulations CUREPORT INC (US) 2018-02-20 — — US claimed
EP-3265063-A1 DUAL LOADED LIPOSOMAL PHARMACEUTICAL FORMULATIONS Cureport, Inc. (US) 2018-01-10 — — EP claimed
EP-3265059-A1 COMBINATION LIPOSOMAL PHARMACEUTICAL FORMULATIONS Cureport Inc. (US) 2018-01-10 — — EP claimed
US-20160256389-A1 COMBINATION LIPOSOMAL PHARMACEUTICAL FORMULATIONS CUREPORT INC (US) 2016-09-08 — — US claimed
EP-1289642-B2 NANOCAPSULES HAVING A POLYELECTROLYTE ENVELOPE CAPSULUTION PHARMA AG (DE) 2012-10-10 — — EP claimed
US-7763275-B2 Template particles are supplied in aqueous medium, electrically charged with polyelectrolyte, recharged without separation or washing steps using second polyelectrolyte having complementary charge with respect to first NOVOSOM AG (DE) 2010-07-27 — — US claimed
US-20090304801-A1 AEROSOL AND INJECTABLE FORMULATIONS OF NANOPARTICULATE BENZODIAZEPINE ELAN PHARMA INTERNATIONAL LIMITED 2009-12-10 — — US claimed
EP-1663158-A2 SPECIFIC DELIVERY OF DRUGS TO THE BRAIN BAXTER INTERNATIONAL INC. (US) 2006-06-07 — — EP claimed
EP-1628641-A2 SOLID PARTICLES COMPRISING AN ANTICONVULSANT OR AN IMMUNOSUPPRESSIVE COATED WITH ONE OR MORE SURFACE MODIFIERS BAXTER INTERNATIONAL INC. (US) 2006-03-01 — — EP claimed
EP-1289642-B1 NANOCAPSULES HAVING A POLYELECTROLYTE ENVELOPE NOVOSOM AG (DE) 2006-02-08 — — EP claimed
US-20050244503-A1 Small-particle pharmaceutical formulations of antiseizure and antidementia agents and immunosuppressive agents BAXTER HEALTHCARE S.A. (CH) 2005-11-03 — — US claimed
US-20050048002-A1 Dispersion; controlling particle size; preabsorption of drug by cells before administering; transferring to brain BAXTER INTERNATIONAL INC. 2005-03-03 — — US claimed
WO-2004112747-A2 SPECIFIC DELIVERY OF DRUGS TO THE BRAIN BAXTER INTERNATIONAL INC. (US) 2004-12-29 — — WO claimed
WO-2004103348-A2 SOLID PARTICLES COMPRISING AN ANTICONVULSANT OR AN IMMUNOSUPPRESSIVE COATED WITH ONE OR MORE SURFACE MODIFIERS BAXTER INTERNATIONAL INC. (US) 2004-12-02 — — WO claimed
US-20030157181-A1 Nanocapsules having a polyelectrolyte envelope CAPSULUTION PHARMA AG (DE) 2003-08-21 — — US claimed
EP-1289642-A1 NANOCAPSULES HAVING A POLYELECTROLYTE ENVELOPE Novosom AG (DE) 2003-03-12 — — EP claimed
WO-2001064330-A1 NANOCAPSULES HAVING A POLYELECTROLYTE ENVELOPE NOVOSOM AG (DE) 2001-09-07 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090304801-A1 AEROSOL AND INJECTABLE FORMULATIONS OF NANOPARTICULATE BENZODIAZEPINE GABRA1, GABRA4, GABRA6 USP2 1555/4885CYP46A1 1278/4885LMNA 1020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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