Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111810 | 0.81 | GPR3 (0.42) | GPR3MAPTMEN1KMT2APOLB | |
| SCHEMBL28245430 | 0.80 | GPR3 (0.48) | GPR3MAPTMEN1KMT2APOLB | |
| SCHEMBL21692521 | 0.76 | SLC22A12 (0.36) | GPR3MAPTMEN1KMT2AMCL1 | |
| SCHEMBL24871562 | 0.76 | AR (0.33) | ARIMPDH2RAB9A | |
| SCHEMBL24860131 | 0.75 | AR (0.30) | ARSLC22A12 | |
| SCHEMBL24871693 | 0.75 | AR (0.33) | AR | |
| SCHEMBL1636538 | 0.74 | GPR3 (0.68) | GPR3MAPTMEN1KMT2APOLB | |
| SCHEMBL24871555 | 0.72 | IMPDH2 (0.34) | GPR3MAPTMEN1KMT2APOLB | |
| SCHEMBL21693075 | 0.72 | ESR2 (0.38) | GPR3MCL1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL21692645 | 0.72 | SLC22A12 (0.35) | GPR3MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115295879-A | Dibenzothiophene electrolyte additive, electrolyte and lithium battery | 陕西奥林波斯电力能源有限责任公司 | 2022-11-04 | — | — | CN | disclosed |
| EP-2121706-A1 | TETRAHYDROQUINOLINE DERIVATIVES AND USE OF SAME FOR TREATING CANCER | Merck Patent GmbH (DE) | 2009-11-25 | — | — | EP | disclosed |
| EP-2121684-A1 | SUBSTITUTED TETRAHYDROPYRROLOQUINOLINES | Merck Patent GmbH (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008113452-A1 | SUBSTITUTED TETRAHYDROPYRROLOQUINOLINES | MERCK PATENT GMBH (DE) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008113456-A1 | TETRAHYDROQUINOLINE DERIVATIVES AND USE OF SAME FOR TREATING CANCER | MERCK PATENT GMBH (DE) | 2008-09-25 | — | — | WO | disclosed |
| EP-1885702-A2 | QUINAZOLINONES | Merck Patent GmbH (DE) | 2008-02-13 | — | — | EP | disclosed |
| CN-1976936-A | Tetrahydroquinolines | MERCK PATENT GMBH (DE) | 2007-06-06 | — | — | CN | disclosed |
| CN-1902190-A | 2- (hetero) aryl-substituted tetrahydroquinoline derivatives | MERCK PATENT GMBH (DE) | 2007-01-24 | — | — | CN | disclosed |
| WO-2006125555-A2 | QUINAZOLINONES | MERCK PATENT GMBH (DE) | 2006-11-30 | — | — | WO | disclosed |