Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794135 | 0.89 | NPC1 (0.48) | NPC1POLBALDH1A1MAPTDGAT2 | |
| SCHEMBL9018014 | 0.85 | NPC1 (0.52) | NPC1POLBALDH1A1MAPTDGAT2 | |
| SCHEMBL15244373 | 0.82 | NPC1 (0.62) | NPC1POLBALDH1A1MAPTDGAT2 | |
| SCHEMBL3692138 | 0.81 | NPC1 (0.56) | NPC1POLBALDH1A1MAPTDGAT2 | |
| SCHEMBL3692136 | 0.78 | NPC1 (0.58) | NPC1POLBALDH1A1MAPTDGAT2 | |
| SCHEMBL9018351 | 0.78 | NPC1 (0.58) | NPC1POLBALDH1A1MAPTDGAT2 | |
| SCHEMBL5630578 | 0.77 | NPC1 (0.52) | NPC1POLBALDH1A1MAPTDGAT2 | |
| SCHEMBL3689970 | 0.77 | NPC1 (0.58) | NPC1POLBALDH1A1MAPTDGAT2 | |
| SCHEMBL15244314 | 0.76 | NPC1 (0.57) | NPC1POLBALDH1A1MAPTDGAT2 | |
| SCHEMBL3761522 | 0.76 | POLB (0.57) | NPC1POLBALDH1A1MAPTDGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507761-B1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | MERIAL INC (US) | 2016-02-24 | — | — | EP | disclosed |
| US-7476685-B2 | Pyridine carboxamide derivatives and their use as pesticides | MERIAL LIMITED (US) | 2009-01-13 | — | — | US | disclosed |
| CN-101230038-A | Pyridine carboxamide derivatives and their use as pesticides | BAYER CROPSCIENCE GMBH (DE) | 2008-07-30 | — | — | CN | disclosed |
| CN-100378076-C | Pyridinecarboxamide derivatives and their use as pesticides | BAYER CROPSCIENCE GMBH (DE) | 2008-04-02 | — | — | CN | disclosed |
| US-20060166991-A1 | Pyridine carboxamide derivatives and their use as pesticides | BAYER CROPSCIENCE GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
| CN-1653048-A | Pyridinecarboxamide derivatives and their use as pesticides | BAYER CROPSCIENCE GMBH (DE) | 2005-08-10 | — | — | CN | disclosed |
| EP-1507761-A1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | Bayer CropScience GmbH (DE) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003097604-A9 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2004-05-06 | — | — | WO | disclosed |
| WO-2003097604-A1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166991-A1 | Pyridine carboxamide derivatives and their use as pesticides | DDT, ACHE, CYCS | NPC1 4667/4885POLB 4540/4885ALDH1A1 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.