SCHEMBL443135

SCHEMBL443135

CCN(C)c1ccc(C(c2ccccc2)(c2ccccc2)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.42
ALDH1A1 P00352 8/20 0.40
TSHR P16473 4/20 0.40
HSD17B10 Q99714 3/20 0.40
MAPK1 P28482 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
RELA Q04206 1/20 0.40
NR1H2 P55055 2/20 0.40
NR1H3 Q13133 2/20 0.40
ALOX15 P16050 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
RAB9A P51151 3/20 0.38
HPGD P15428 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10775477 0.87 SLC2A1 (0.54) SLC2A1ALDH1A1TSHRHSD17B10MAPK1
SCHEMBL9780514 0.87 SLC2A1 (0.54) SLC2A1ALDH1A1TSHRHSD17B10MAPK1
SCHEMBL5922062 0.87 SLC2A1 (0.54) SLC2A1ALDH1A1TSHRHSD17B10MAPK1
SCHEMBL12382311 0.86 CNR2 (0.47) SLC2A1ALDH1A1TSHRHSD17B10MAPK1
SCHEMBL10933832 0.83 NR1H2 (0.59) SLC2A1ALDH1A1TSHRHSD17B10MAPK1
SCHEMBL762882 0.80 ALDH1A1 (0.61) SLC2A1ALDH1A1TSHRHSD17B10MAPK1
SCHEMBL9718478 0.78 ALDH1A1 (0.65) SLC2A1ALDH1A1TSHRHSD17B10MAPK1
SCHEMBL12342194 0.77 CNR2 (0.53) ALDH1A1TSHRMAPK1TDP1NR1H2
SCHEMBL3490254 0.77 CNR2 (0.53) ALDH1A1TSHRMAPK1TDP1NR1H2
SCHEMBL3490247 0.77 CNR2 (0.53) ALDH1A1TSHRMAPK1TDP1NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8809543-B2 Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus RICOH COMPANY, LTD. (JP) 2014-08-19 US disclosed
US-20120064443-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING METHOD, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FOR ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2012-03-15 US disclosed