SCHEMBL762882

SCHEMBL762882

CCN(C)c1ccc(N(C)C)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.61
TSHR P16473 7/20 0.61
ALOX15 P16050 3/20 0.61
HSD17B10 Q99714 3/20 0.61
MAPK1 P28482 5/20 0.52
CYP3A4 P08684 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
ADRA2A P08913 2/20 0.52
ADRA2B P18089 2/20 0.52
ADRA2C P18825 2/20 0.52
CYP2A6 P11509 1/20 0.48
CYP2A13 Q16696 1/20 0.48
TP53 P04637 2/20 0.48
RAB9A P51151 1/20 0.46
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL762061 0.93 ALDH1A1 (0.52) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL10330355 0.91 ADRA2A (0.58) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL12679045 0.89 ALDH1A1 (0.74) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL17228666 0.87 ALDH1A1 (0.61) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL13069328 0.87 SLC2A1 (0.55) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL18323114 0.83 ADRA2A (0.52) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL4400993 0.83 ADRA2A (0.52) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL6842262 0.83 HPGD (0.73) ALDH1A1TSHRALOX15MAPK1CYP3A4
SCHEMBL8278827 0.81 ALDH1A1 (0.55) ALDH1A1TSHRALOX15HSD17B10MAPK1
SCHEMBL3949344 0.79 ADRA2A (0.48) ALDH1A1TSHRALOX15HSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220125927-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2022-04-28 US disclosed
US-9716241-B2 Polycyclic dithiophenes BASF SE (DE) 2017-07-25 US disclosed
US-20160104849-A1 POLYCYCLIC DITHIOPHENES BASF SE (DE) 2016-04-14 US disclosed
US-9233930-B2 Polycyclic dithiophenes BASF SE (DE) 2016-01-12 US disclosed
US-20150306039-A1 IMPROVED NUCLEIC ACID LIPID PARTICLE FORMULATIONS BANK OF AMERICA, N.A. 2015-10-29 US disclosed
US-20150306039-A1 IMPROVED NUCLEIC ACID LIPID PARTICLE FORMULATIONS BANK OF AMERICA, N.A. 2015-10-29 US disclosed
US-20150273068-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2015-10-01 US disclosed
US-20150273068-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2015-10-01 US disclosed
US-8221906-B2 Electroluminescent polymers for electronic applications BASF SE (DE) 2012-07-17 US disclosed
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-20120097935-A1 POLYCYCLIC DITHIOPHENES BASF SE (DE) 2012-04-26 US disclosed
US-8138303-B2 Polymers BASF SE (DE) 2012-03-20 US disclosed
US-20100249349-A1 Novel Polymers UDC IRELAND LIMITED (IE) 2010-09-30 US disclosed
US-20090309068-A1 NOVEL ELECTROLUMINESCENT POLYMERS FOR ELECTRONIC APPLICATIONS UDC IRELAND LIMITED (IE) 2009-12-17 US disclosed
US-4840879-A COLORED LATENT IMAGE IS REACTION PRODUCT OF COUPLER AND AROMATIC PRIMARY AMINO COLOR DEVELOPER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249349-A1 Novel Polymers OCIAD2, OCIAD1, SLCO4C1 ALDH1A1 478/4885TSHR 4848/4885ALOX15 328/4885
US-20150273068-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP ALDH1A1 3151/4885TSHR 2733/4885ALOX15 196/4885
US-20160104849-A1 POLYCYCLIC DITHIOPHENES C1R, C2CD5, CBR3 ALDH1A1 3722/4885TSHR 256/4885ALOX15 3380/4885
US-20220125927-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP ALDH1A1 3151/4885TSHR 2733/4885ALOX15 196/4885
US-20120097935-A1 POLYCYCLIC DITHIOPHENES C1R, IPO5, C2CD5 ALDH1A1 3736/4885TSHR 602/4885ALOX15 2316/4885
US-20150306039-A1 IMPROVED NUCLEIC ACID LIPID PARTICLE FORMULATIONS LIPA, NPC1L1, CETP ALDH1A1 2297/4885TSHR 3683/4885ALOX15 474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.