Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430723 | 0.85 | IDH1 (0.42) | GAAKDM4ELMNASMN1; SMN2KMT2A | |
| SCHEMBL8579730 | 0.73 | KMT2A (0.49) | HSD17B10TSHRUSP2MAPK1L3MBTL1 | |
| SCHEMBL1873977 | 0.72 | ALDH1A1 (0.68) | TSHRMAPK1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL112999 | 0.72 | ALDH1A1 (0.68) | TSHRMAPK1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL1332625 | 0.72 | ALDH1A1 (0.68) | TSHRMAPK1L3MBTL1LMNASMN1; SMN2 | |
| Benzene SCHEMBL28160801 | 0.72 | ALDH1A1 (0.68) | TSHRMAPK1L3MBTL1LMNASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27681752 | 0.70 | ALDH1A1 (0.66) | TSHRMAPK1L3MBTL1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28243605 | 0.70 | ALDH1A1 (0.66) | TSHRMAPK1L3MBTL1LMNASMN1; SMN2 | |
| Water SCHEMBL27679105 | 0.70 | ALDH1A1 (0.66) | TSHRMAPK1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL24129893 | 0.70 | HSD17B10 (0.56) | HSD17B10TSHRUSP2MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125739-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008079371-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |