Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4175707 | 0.90 | DPP4 (0.38) | DPP4GRM2ABL1MAPK14CYP1A2 | |
| SCHEMBL4433037 | 0.88 | ABL1 (0.34) | DPP4GRM2ABL1MAPK14 | |
| SCHEMBL27781264 | 0.88 | ABL1 (0.32) | DPP4GRM2ABL1MAPK14 | |
| SCHEMBL4171143 | 0.85 | ABL1 (0.33) | DPP4GRM2ABL1MAPK14 | |
| SCHEMBL4437511 | 0.84 | TAAR1 (0.43) | TAAR1DPP4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4172328 | 0.78 | PDE2A (0.43) | ABL1 | |
| SCHEMBL4181231 | 0.78 | CYP1A2 (0.41) | MAPK14CYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL4436584 | 0.77 | CLK4 (0.34) | ABL1MAPK14CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4178794 | 0.76 | ABL1 (0.34) | DPP4GRM2ABL1MAPK14CYP1A2 | |
| SCHEMBL4177843 | 0.75 | GRM2 (0.37) | GRM2ABL1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137186-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | Amgen Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008118468-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2008-10-02 | — | — | WO | disclosed |