SCHEMBL4431469

SCHEMBL4431469

CCCCc1cc(C(=O)O)c(C(=O)O)c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 1/20 0.46
CXCL12 P48061 1/20 0.46
DHODH Q02127 1/20 0.46
BID P55957 3/20 0.46
MCL1 Q07820 3/20 0.46
PPARA Q07869 3/20 0.46
BCL2L1 Q07817 2/20 0.46
BAK1 Q16611 2/20 0.46
KAT8 Q9H7Z6 2/20 0.46
PPARG P37231 2/20 0.46
EP300 Q09472 1/20 0.46
KAT2A Q92830 1/20 0.46
KAT2B Q92831 1/20 0.46
KAT5 Q92993 1/20 0.46
SAE1 Q9UBE0 1/20 0.46
AGTR1 P30556 2/20 0.45
KDM4E B2RXH2 1/20 0.44
GABRP O00591 1/20 0.44
GABRD O14764 1/20 0.44
GABRA1 P14867 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11320748 0.88 DHODH (0.49) HMGB1CXCL12DHODHBIDMCL1
SCHEMBL12447840 0.85 HMGB1 (0.53) HMGB1CXCL12KDM4E
SCHEMBL14135763 0.85 HMGB1 (0.67) HMGB1CXCL12DHODHMCL1BCL2L1
SCHEMBL6332056 0.80 CNR2 (0.56) HMGB1CXCL12DHODHAGTR1KDM4E
SCHEMBL2531533 0.79 GABRP (0.50) BIDMCL1PPARABCL2L1BAK1
SCHEMBL27599806 0.77 BID (0.42) DHODHBIDMCL1PPARABCL2L1
SCHEMBL29138978 0.77 AGTR1 (0.51) DHODHBIDMCL1PPARABCL2L1
SCHEMBL30732531 0.77 AGTR1 (0.51) DHODHBIDMCL1PPARABCL2L1
SCHEMBL14989220 0.76 GABRP (0.48) BIDMCL1PPARABCL2L1BAK1
SCHEMBL1121887 0.76 GABRP (0.48) BIDMCL1PPARABCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1644437-A4 LOW GLOW OLEFIN FERRO CORP (US) 2009-02-18 EP disclosed
EP-1599544-A4 GLASS REINFORCED NYLON BLEND WITH IMPROVED KNITLINE STRENGTH FERRO CORP (US) 2007-05-02 EP disclosed
US-7176607-B2 Light fixture with reflective polymeric composition and pigment package FERRO CORPORATION (US) 2007-02-13 US disclosed
EP-1579147-A4 LIGHT REFLECTING POLYMERIC COMPOSITIONS FERRO CORP (US) 2006-05-17 EP disclosed
EP-1644437-A1 LOW GLOW OLEFIN FERRO CORPORATION (US) 2006-04-12 EP disclosed
US-7026391-B2 Polymer compositions comprising polyolefins and reaction products of a polyolefin and an unsaturated carboxylic reagent and articles made therefrom FERRO CORPORATION (US) 2006-04-11 US disclosed
EP-1599544-A1 GLASS REINFORCED NYLON BLEND WITH IMPROVED KNITLINE STRENGTH FERRO CORPORATION (US) 2005-11-30 EP disclosed
EP-1579147-A1 LIGHT REFLECTING POLYMERIC COMPOSITIONS FERRO CORPORATION (US) 2005-09-28 EP disclosed
US-20050095534-A1 Light reflecting polymeric compositions FERRO CORPORATION (US) 2005-05-05 US disclosed
WO-2005007736-A1 LOW GLOW OLEFIN FERRO CORPORATION (US) 2005-01-27 WO disclosed
US-20030004245-A1 Polymer compositions comprising polyolefins and reaction products of a polyolefin and an unsaturated carboxylic reagent and articles made therefrom LYONDELLBASELL ADVANCED POLYMERS INC. 2003-01-02 US disclosed
US-6465558-B2 MIXTURE OF TERPENE, ALDEHYDE, KETONE OR AROMATIC SOLVENT FERRO CORPORATION 2002-10-15 US disclosed
WO-2002062886-A1 SOLVENT BASED ADHESIVE COMPOSITION FERRO CORPORATION (US) 2002-08-15 WO disclosed
EP-0847410-B1 ONE-PART, LOW VISCOSITY, MOISTURE CURABLE COMPOSITION TREMCO INC (US) 2001-11-21 EP disclosed
US-20010034386-A1 Solvent based adhesive composition FERRO CORPORATION 2001-10-25 US disclosed
WO-1999046321-A1 POLYMER COMPOSITIONS COMPRISING POLYOLEFINS AND REACTION PRODUCTS OF A POLYOLEFIN AND AN UNSATURATED CARBOXYLIC REAGENT AND ARTICLES MADE THEREFROM FERRO CORPORATION (US) 1999-09-16 WO disclosed
US-5714563-A USING AN ACETOACETATE FUNCTIONAL COMPOUND AND A POLYISOCYANANTE; RAPID CURING; STORAGE STABILITY TREMCO, INC 1998-02-03 US disclosed
US-5317059-A Impact-resistant polymer blends of olefin polymers, polyamides, and terpolymer compatibilizers FERRO CORPORATION (US) 1994-05-31 US disclosed
US-5278231-A Comprising hydrogenated block copolymer FERRO CORPORATION (US) 1994-01-11 US disclosed
WO-1992022607-A1 HIGH SURFACE ENERGY POLYOLEFIN BLEND COMPOSITIONS THE FERRO CORPORATION (US) 1992-12-23 WO disclosed