Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13692258 | 0.97 | NFKB1 (0.44) | LMNATHRBBLMKMT2ANPSR1 | |
| SCHEMBL19925599 | 0.97 | LMNA (0.43) | LMNATHRBBLMKMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL25202141 | 0.95 | BLM (0.46) | LMNATHRBBLMKMT2ANPSR1 | |
| SCHEMBL31040378 | 0.95 | LMNA (0.46) | LMNATHRBBLMKMT2ANPSR1 | |
| SCHEMBL25351334 | 0.95 | LMNA (0.46) | LMNATHRBBLMKMT2ANPSR1 | |
| SCHEMBL31040390 | 0.95 | LMNA (0.46) | LMNATHRBBLMKMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL25354101 | 0.93 | BLM (0.44) | LMNATHRBBLMKMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL25353130 | 0.93 | BLM (0.44) | LMNATHRBBLMKMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL25355836 | 0.93 | BLM (0.44) | LMNATHRBBLMKMT2ANPSR1 | |
| SCHEMBL31040409 | 0.92 | LMNA (0.48) | LMNATHRBBLMKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110461860-A | CALICHEAMICIN DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER | 2019-11-15 | — | — | CN | disclosed |
| WO-2009129385-A1 | CATIONIC LIPIDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2009-10-22 | — | — | WO | disclosed |