Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.64 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115002 | 0.85 | PPARG (0.71) | PARP10MAPTPLA2G4BNR4A1NR4A2 | |
| SCHEMBL138162 | 0.85 | ALOX15 (0.68) | PARP10MAPTTP53SMN1; SMN2FFAR1 | |
| SCHEMBL1395785 | 0.84 | PARP10 (0.68) | PARP10MAPTNR4A1NR4A2NR4A3 | |
| SCHEMBL7908824 | 0.83 | PARP10 (0.54) | PARP10MAPTTP53NR4A1NR4A2 | |
| SCHEMBL4432738 | 0.83 | MAOB (0.71) | PARP10NR4A2MAOBMAOACA12 | |
| Hydrochloric Acid SCHEMBL1291208 | 0.83 | ALOX15 (0.65) | PARP10MAPTTP53GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27524256 | 0.83 | ALOX15 (0.65) | PARP10MAPTTP53GAASMN1; SMN2 | |
| SCHEMBL29145072 | 0.83 | ALOX15 (0.65) | PARP10MAPTTP53GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7004811 | 0.83 | MAPT (0.50) | PARP10MAPTTP53PLA2G4BNR4A1 | |
| SCHEMBL10506137 | 0.82 | MEN1 (0.58) | PARP10MAPTTP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085145-B | Preparation method of R- (+) -2- (4-hydroxyphenoxy) methyl propionate | 苏州开元民生科技股份有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-114085145-A | Environment-friendly preparation method of R- (+) -2- (4-hydroxyphenoxy) methyl propionate | 苏州开元民生科技股份有限公司 | 2022-02-25 | — | — | CN | claimed |
| EP-1761480-B1 | MAO-B INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-02-18 | — | — | EP | claimed |
| CN-114085145-B | Preparation method of R- (+) -2- (4-hydroxyphenoxy) methyl propionate | 苏州开元民生科技股份有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-109153655-B | Novel N-acylurea derivatives and compositions comprising the same for preventing or treating cardiovascular diseases | 高丽大学校产学协力团 | 2022-09-30 | — | — | CN | disclosed |
| CN-114085145-A | Environment-friendly preparation method of R- (+) -2- (4-hydroxyphenoxy) methyl propionate | 苏州开元民生科技股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-114085145-A | Environment-friendly preparation method of R- (+) -2- (4-hydroxyphenoxy) methyl propionate | 苏州开元民生科技股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| EP-2316834-A1 | Thiadiazoles or oxadiazoles and their use as inhibitors of JAK protein kinase | Vertex Pharmaceuticals Incorporated (US) | 2011-05-04 | — | — | EP | disclosed |
| EP-1761480-B1 | MAO-B INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-02-18 | — | — | EP | disclosed |