Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.35 |
| ▸ | FABP7 | O15540 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509899 | 0.81 | SIRT2 (0.32) | BACE1CASP3MDM2 | |
| SCHEMBL5508572 | 0.81 | SIRT2 (0.32) | BACE1CASP3MDM2 | |
| SCHEMBL27042592 | 0.80 | CASP3 (0.35) | BACE1KMT2ACASP3FABP5FABP7 | |
| SCHEMBL5508568 | 0.80 | BACE1 (0.31) | BACE1MDM2 | |
| SCHEMBL7433217 | 0.79 | MDM2 (0.34) | BACE1KMT2ACASP3MDM2 | |
| SCHEMBL4430175 | 0.78 | TNF (0.32) | BACE1CASP3 | |
| SCHEMBL1557276 | 0.75 | PPARG (0.41) | BACE1KMT2ACASP3 | |
| SCHEMBL289035 | 0.75 | FABP5 (0.40) | KMT2ACASP3FABP5FABP7CA1 | |
| SCHEMBL27527132 | 0.74 | CASP3 (0.38) | KMT2ACASP3FABP5FABP7CA1 | |
| SCHEMBL5141642 | 0.73 | CASP3 (0.34) | BACE1KMT2ACASP3FABP5FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125695-A2 | NITRIC OXIDE DONOR COMPOUNDS | Nicox S.A. (FR) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |