Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27527132 | 0.81 | CASP3 (0.38) | FABP5FABP7CASP3CA1CA2 | |
| SCHEMBL27042592 | 0.80 | CASP3 (0.35) | FABP5FABP7CASP3CA1CA2 | |
| SCHEMBL7438474 | 0.78 | TLR2 (0.36) | FABP5FABP7CASP3KMT2APPARG | |
| SCHEMBL4740141 | 0.77 | KMT2A (0.38) | FABP5FABP7CASP3CA1CA2 | |
| SCHEMBL5141642 | 0.77 | CASP3 (0.34) | FABP5FABP7CASP3CA1CA2 | |
| SCHEMBL12466708 | 0.77 | KMT2A (0.49) | FABP5FABP7CASP3KMT2ACYP1A2 | |
| SCHEMBL1556697 | 0.77 | OPRM1 (0.38) | CASP3KMT2A | |
| SCHEMBL29913804 | 0.76 | FABP5 (0.47) | FABP5FABP7CASP3CA1CA2 | |
| SCHEMBL4432786 | 0.75 | BACE1 (0.38) | FABP5FABP7CASP3CA1CA2 | |
| SCHEMBL1557276 | 0.75 | PPARG (0.41) | CASP3KMT2APPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BioLab Corporation (JP) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128685-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2010-11-11 | — | — | WO | disclosed |